Advanced Science, EarlyView.Grounded in real biological RNA‐seq data, the framework benchmarks ten differential transcript usage (DTU) methods across short‐read bulk, long‐read bulk, long‐read single‐cell, and long‐read spatial transcriptomics. By integrating reference transcript sets with ranked DTU results, the Transcript Set Enrichment Score (TSES) identifies data‐type ...
Chenxing Zhang +6 more
wiley +1 more source
Depressive Symptoms, Insomnia-Related Difficulties and Self-Rated Health Among Community-Dwelling Adults Aged 40 Years and Older in Western China: A Cross-Sectional Structural Equation Modelling Study. [PDF]
Healthcare (Basel)Yao L, Tham J.
europepmc +1 more source
SAV1 in Cooperation With FKBP52 Participates in Implantation
Advanced Science, EarlyView.The MST‐SAV1 complex modulates FKBP52 phosphorylation to fine‐tune PR activity, ensuring timely uterine transition to receptivity under estrogen signaling for implantation. Stromal SAV1 scaffolds MST1/2‐mediated FKBP52 phosphorylation via noncanonical Hippo to promote PR activity.
Yuhan Shao +10 more
wiley +1 more source
Comparing aggregated and nonlinear measures of coordinative behaviors in immediate responder first aid groups: a controlled experimental simulation study. [PDF]
Adv Simul (Lond)Brodin W +3 more
europepmc +1 more source
Advanced Science, EarlyView.By exploiting multiscale hydrogen‐bonding interactions between HFPD and TOCNF, the composite simultaneously achieves a high piezoelectric coefficient (14.0 pC·N−1), outstanding flexibility (100 000 bending cycles), water‐assisted recyclability, excellent biodegradability, and sensitive wearable/implantable sensing for motion, speech, and Morse code ...
Tingshuai Luo +9 more
wiley +1 more source
Interview dataset: Encouraging the development of industrial symbiosis networks in Slovenia - transition to the circular economy. [PDF]
Data BriefUršič ED.
europepmc +1 more source
Advanced Science, EarlyView.PTBP1‐mediated alternative splicing drives a pathogenic switch to the DNAJB6b isoform in everolimus‐resistant clear cell renal cell carcinoma. This splicing event programs a positive feedback loop including EIF4B/PKIB/AKT/mTOR, promoting aggressive therapy resistance.
Xiu‐wu Pan +18 more
wiley +1 more source
Future-oriented careers: what social and emotional capabilities do medical students need? A qualitative analysis. [PDF]
Front Med (Lausanne)Yang F, Yang T, Wang D, Li Y.
europepmc +1 more source
Dual Repression by IPA1 Fine‐Tunes OsbZIP79‐Mediated Salt Tolerance in Rice
Advanced Science, EarlyView.Dual repression by IPA1 fine‐tunes OsbZIP79‐mediated salt tolerance in rice: direct transcriptional inhibition under normal conditions and salt‐induced degradation under stress. This dual mechanism activates OsbZIP79 to regulate Na+/K+ homeostasis and redox balance via downstream genes, enabling optimal salt stress response.
Hui Wang +12 more
wiley +1 more source