Results 181 to 190 of about 267,073 (258)

Extracellular Vesicles Modulation by an Adiponectin Receptor Agonist Provides Cardioprotection for Myocardial Ischemic Injury

open access: yesAdvanced Healthcare Materials, EarlyView.
This study demonstrates that ALY688, a drug mimicking the heart‐protective hormone adiponectin, reduces myocardial ischemia injury. ALY688 increases the production of extracellular vesicles, which carry protective cargo including adiponectin itself.
Jialing Tang   +13 more
wiley   +1 more source

Physicochemical Reinforcement Unlocks Sterilization‐Stable Anisotropic Hydrogels for Cell‐Compatible Mock Arteries

open access: yesAdvanced Healthcare Materials, EarlyView.
ABSTRACT In vitro arterial models offer ethical and robust alternatives for vascular research but require cytocompatible materials that replicate physiological mechanics. Poly(vinyl alcohol) (PVA) hydrogels produced by directional freezing and salting‐out (PVA DFSO) are anisotropic yet lack stability for cell culture. Herein, methacrylated PVA (PVA‐MA)
Javiera Sanhueza Ortega   +4 more
wiley   +1 more source

Recapitulating Endochondral Ossification for Bone Repair: From Development to Engineering Strategy

open access: yesAdvanced Healthcare Materials, EarlyView.
This review summarizes the developmental basis of endochondral ossification (ECO) and its applications in bone tissue engineering (BTE). It first outlines the key biological processes and signaling pathways underlying ECO, then discusses biomaterial‐based engineering strategies derived from these principles, and finally highlights future directions for
Yiqi Su   +8 more
wiley   +1 more source

The VALUE Study: Exploring the Value of a Clinical Ethics Consultation Service at the "A. Gemelli" Hospital. [PDF]

open access: yesHealthcare (Basel)
Masilla SS   +7 more
europepmc   +1 more source

Simultaneous Electrochemical Detection of NGF and proNGF Under Native Conditions Using Molecularly Imprinted Polymers: Toward Point‐of‐Care Diagnosis of Alzheimer's Disease

open access: yesAdvanced Healthcare Materials, EarlyView.
This study relies on the development of a new sensor that can detect two closely related proteins involved in Alzheimer's disease at the same time. Unlike traditional methods, it works in natural conditions and does not require sample pretreatment. The device is highly sensitive and was successfully tested on patient samples, offering promises for ...
Giulia Siciliano   +12 more
wiley   +1 more source

Long‐Term Hydrophilic, Anti‐Clotting, and Anti‐Fibrotic Dynamic Covalent Silicone‐Based Biomaterials

open access: yesAdvanced Healthcare Materials, EarlyView.
Dynamic covalent crosslinking of a Schiff‐base silicone elastomer with hydrazide‐functionalized polymers is demonstrated to improve the long‐term hydrophilicity as well as the anti‐fouling and anti‐clotting properties of PDMS implants. The hydrazone‐functionalized material prevents hydrophobic recovery, resists clotting, and significantly reduces ...
Norma A. Garza Flores   +12 more
wiley   +1 more source

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