Results 241 to 250 of about 704,066 (290)

ISPOR's “Code of Ethics for Researchers”: Is It Ethical?

, 2004
Richard Milne
openalex   +1 more source

METTL14‐Mediated M6A Modification of LINC01094 Induces Glucose Metabolic Reprogramming in Breast Cancer by Recruiting the PKM2/JMJD5 Complex

Advanced Science, EarlyView.
METTL14/IGF2BP2‐mediated m6A modification drives LINC01094 upregulation in BC. Then, LINC01094 interacts with PKM2 monomers to promote their dimerization, while serving as a flexible scaffold to facilitate the assembly of the PKM2/JMJD5 complex, synergistically stabilizing PKM2 dimers and enhancing their nuclear translocation.
Mengqi Wang, Zhaoxin Gao, Ruinan Zhao, Pan Zhou, Jingxi Chen, Hui Zhang, Yawen Wang, Wenjie Zhu, Peng Gao   +8 more
wiley   +1 more source

Corrigendum to "Farmers' willingness to pay for metal silo cereal storage technology in northeast Ethiopia" [Heliyon Volume 9, Issue 8, August 2023, Article e18223]. [PDF]

Heliyon
Teshome DG, Mussa EC, Dessie AB, Abate TM, Ayalew DY.   +4 more
europepmc   +1 more source

LRRC8A Regulates Outer Hair Cell Volume and Electromotility and is Required for Hearing

Advanced Science, EarlyView.
This study identifies LRRC8A‐dependent volume‐regulated anion channels (VRACs) as essential for cochlear outer hair cells' electromotility and auditory signal amplification. LRRC8A deficiency disrupts cell volume control, impairs auditory sensitivity, and causes deafness, while targeted LRRC8A re‐expression restores auditory function.
Shengnan Wang, Yuehui Xi, Qiaojun Fang, Sai Shi, Fei Wang, Fuyu Xian, Zhongyang Zhang, Yuxin Yang, Xishuo Jin, Xiaomin Wang, Chen Cao, Hailin Zhang, Nikita Gamper, Zhigang Xu, Haitao Shen, Ping Lv   +15 more
wiley   +1 more source

Dilemma of missing specific disease codes: an approach to assess the incidence and prevalence of a rare nephrology disease. [PDF]

BMC Nephrol
Roll M, Gladbach A, Selinger I, Hardt T, Himmelhaus H, Jacob C, Stremel T, Theil J, Floege J.   +8 more
europepmc   +1 more source

Cryptic Splicing of GAP43 mRNA is a Novel Hallmark of TDP‐43‐Associated ALS and AD

Advanced Science, EarlyView.
TDP‐43 dysfunction disrupts RNA processing, inducing cryptic exon 4a1 inclusion in GAP43 and reducing its protein levels. This aberrant splicing impairs axonal regeneration and contributes to neurodegeneration in ALS and AD. RNA‐seq of patient brains reveals GAP43 downregulation and 4a1 upregulation, identifying cryptic exon 4a1 as a potential ...
Mingming Yang, Qi Wang, Dongkun Kang, Shijia Wang, Yanli Jiang, Jian‐Zhi Wang, Chen Ming, Rong Liu, Jianlan Gu, Xiaochuan Wang   +9 more
wiley   +1 more source

Falling and Landing Framework (FLF): A Consensus on a Novel Falling and Landing Video Analysis Framework for Use Across Rugby Codes. [PDF]

Eur J Sport Sci
Petrie FJ, Woodward JS, McLeod S, West SW, Salmon D, Gardner AJ, Shill IJ, Romanchuk J, Dane K, Kitchin M, Jones B, Mackintosh KA, Starbuck C, Hendricks S, Philips G, Jones S, Tierney G, McNarry MA.   +17 more
europepmc   +1 more source

The research group IDEA Forum. Projects, code of ethics and epistemological framework

, 2005
Fòrum Idea
openalex   +2 more sources

Exome Sequencing Reveals the Genetic Architecture of Non‐syndromic Orofacial Clefts and Identifies BOC as a Novel Causal Gene

Advanced Science, EarlyView.
Nonsyndromic orofacial clefts (NSOFCs) are the most common craniofacial defects. Exome sequencing of 214 sporadic cases sheds new light on its genetic architecture and identifies many candidate pathogenic variants. Furthermore, functional studies establish BOC as a novel causal gene and reveal an unusual two‐locus model of inheritance via the epistatic
Qing He, Min Yu, Yuhua Jiao, Yizhu Xu, Xuqin Liang, Wenbin Huang, Linping Xu, Yuxia Hou, Zhanping Ren, Beile Lyu, Zhenwei Qian, Pengpeng Liu, Jing Zhou, Huimei Huang, Chunyan Yin, Huaxiang Zhao, Yi Ding   +16 more
wiley   +1 more source

Building an Ethical Framework for European Pharmacists in e-Pharmacies.

J Med Internet Res
Toma A, Crişan O.
europepmc   +1 more source