Results 51 to 60 of about 704,066 (290)
TRPM8 levels determine tumor vulnerability to channel agonists
Molecular Oncology, EarlyView.TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo +18 more
wiley +1 more source
ECNU Review of Education, 2022 Purpose The new Finnish National Core Curriculum for Early Childhood Education and Care (2018) strongly highlights pedagogical knowledge and practice, demanding teachers to develop their pedagogical thinking, evaluation, judgment, and operating culture ...
Anitta Melasalmi +2 more
doaj +1 more source
Should There Be a Specialized Ethics Code for Death-Penalty Defense Lawyers [PDF]
, 2016 State ethics codes based on the ABA Model Rules of Professional Conduct address lawyers\u27 work in advocacy but do not target lawyers\u27 work in particular areas of advocacy or in other specialized practice areas.
Green, Bruce A.
core +1 more source
Molecular Oncology, EarlyView.The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song +11 more
wiley +1 more source
Análise lexical do Código de Ética Odontológica
Revista de Odontologia da UNESPResumo Introdução O Código de Ética Odontológica (CEO), Resolução CFO-118 de maio de 2012, é um documento que preconiza a atuação ética dos profissionais registrados no Conselho Federal de Odontologia, com a intenção de orientação, reflexão e ...
Cléa Adas Saliba GARBIN +3 more
doaj +1 more source
Codes of Ethics in Research and Experimentation in Man [PDF]
, 1973 Professor Liley\u27s most notable contribution to medicine was the introduction of intrauterine fetal blood transfusion in the management of Rh sensitization. His work has had worldwide recognition.
Liley, A. W.
core +1 more source
Molecular Oncology, EarlyView.In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton +17 more
wiley +1 more source
The commitment of public sector Sweden to codes of ethics
, 2004 This article examines the results of a study conducted of the top 100 public sector units in Sweden. These units are comprised of entities of government, municipalities, and county councils. The aim of the study was to examine and describe the commitment
Callaghan, Michael +2 more
core +1 more source
The role of law and ethics in developing business management as a profession [PDF]
, 2009 Currently, business management is far from being recognised as a profession. This paper suggests that a professional spirit should be developed which could function as a filter of commercial reasoning. Broadly, management will not be organised within the
Buber M. +9 more
core +1 more source
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
Molecular Oncology, EarlyView.GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski +19 more
wiley +1 more source