Results 121 to 130 of about 4,070,895 (341)

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Euclid : modelling massive neutrinos in cosmology — a code comparison [PDF]

, 2022
Euclid Consortium, Adamek, Julian, Angulo, R. E., Christian Arnold, Marco Baldi, Matteo Biagetti, Benjamin Bose, C. Carbone, T. Castro, Jeppe Dakin, K. Dolag, Willem Elbers, Fidler, Christian, C. Giocoli, Steen Hannestad, Farbod Hassani, César Hernández‐Aguayo, K. Koyama, Baojiu Li, Renate Mauland, Pierluigi Monaco, Chiara Moretti, Mota, D. F., Christian Partmann, Gabriele Parimbelli, D. Potter, Aurel Schneider, Sebastian Schulz, Smith, R. E., Volker Springel, Joachim Stadel, Thomas Tram, Matteo Viel, Francisco Villaescusa-Navarro, Winther, H. A., Wright, B. S., Matteo Zennaro, N. Aghanim, Luca Amendola, N. Auricchio, D. Bonino, E. Branchini, M. Brescia, S. Camera, V. Capobianco, Cardone, V. F., J. Carretero, Castander, F. J., M. Castellano, S. Cavuoti, A. Cimatti, R. Clédassou, G. Congedo, L. Conversi, Y. Copin, A. Da Silva, H. Degaudenzi, M. Douspis, F. Dubath, Duncan, C. A. J., X. Dupac, S. Dusini, S. Farrens, S. Ferriol, P. Fosalba, M. Frailis, E. Franceschi, S. Galeotta, B. Garilli, W. Gillard, B. Gillis, A. Grazian, Haugan, S. V., W. Holmes, A. Hornstrup, K. Jahnkę, S. Kermiche, A. Kiessling, M. Kilbinger, T. Kitching, M. Kunz, H. Kurki‐Suonio, Lilje, P. B., I. Lloro, O. Mansutti, O. Marggraf, F. Marulli, R. Massey, E. Medinaceli, M. Meneghetti, G. Meylan, M. Moresco, L. Moscardini, E. Munari, S.-M Niemi, Padilla, C., S. Paltani, F. Pasian, K Pedersen, Percival, W. J.   +99 more
openalex   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

Coding for Network Coding

, 2007
We consider communication over a noisy network under randomized linear network coding. Possible error mechanism include node- or link- failures, Byzantine behavior of nodes, or an over-estimate of the network min-cut. Building on the work of Koetter and Kschischang, we introduce a probabilistic model for errors.
Montanari, Andrea, Urbanke, Ruediger
openaire   +2 more sources

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Code [PDF]

Psychiatric Services, 2017
openaire   +2 more sources

Contrast-Enhanced Transcranial Color-Coded Sonography in Acute Cerebral Infarction [PDF]

, 2000
Raymond Tak Fai Cheung
openalex   +1 more source