Results 221 to 230 of about 4,009,002 (325)

Differential roles of coding and non-coding transcripts in obesity: insights from RNA-seq analysis of Macaca fascicularis hepatocytes. [PDF]

BMC Genomics
Liu Y, Wang Z, Liu L, Tan Y, Zheng W, Zhang P, Hutchins AP, Lipovich L, Wang W.   +8 more
europepmc   +1 more source

Logarithmic coding leads to adaptive stabilization in the presence of sensorimotor delays [PDF]

Leonardo Demarchi, Monica Coraggioso, Antoine Hubert, Thomas Panier, Ghislaine Morvan-Dubois, Volker Bormuth, Georges Debrégeas   +6 more
openalex   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

FEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde, Unai Alduntzin, Gorka Prieto, Ugo Mayor   +3 more
wiley   +1 more source

Quality of Cancer-Related Clinical Coding in Primary Care in North Central London: Mixed Methods Quality Improvement Project.

J Med Internet Res
Bhuiya A, Roberts G, Tucker K, Bonfield S, Black G.   +4 more
europepmc   +1 more source

Diversity of lncRNAs in the pan-transcriptome of maize inbred lines. [PDF]

BMC Genomics
Pronozin AY, Shmakov NA, Afonnikov DA.
europepmc   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Association between the WHO 2017 and 2022 classification updates and ICD-10 code accuracy in patients with PitNETs: a real-world retrospective study. [PDF]

BMC Endocr Disord
Zhou J, Guo X, Mao X, Duan L, Liao A, Li N, Xing B.   +6 more
europepmc   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Switching Ionization Polarity to Simplify MS/MS Sequencing of Digital Polymers: the Case of Informational Poly(Amino phosphodiester)s. [PDF]

Rapid Commun Mass Spectrom
Sergent I, Roszak I, Lutz JF, Charles L.
europepmc   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source