Results 111 to 120 of about 7,506,861 (344)

Landscape of BRAF transcript variants in human cancer

open access: yesMolecular Oncology, EarlyView.
We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda   +5 more
wiley   +1 more source

The complete mitochondrial DNA sequence of ruffe Acerina cernua

open access: yesMitochondrial DNA. Part B. Resources, 2019
Acerina cernua is a specific percid species that naturally occurs in Xinjiang Irtysh River basin, China. The complete mitochondrial genome of the ruffe A. cernua was first determined (Accession number MK509809), with a total length of 16,677 nucleotides,
Yao-Yao Li   +4 more
doaj   +1 more source

Comprehensive omics‐based classification system in adult patients with B‐cell acute lymphoblastic leukemia

open access: yesMolecular Oncology, EarlyView.
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song   +11 more
wiley   +1 more source

Complete mitochondrial genome data and phylogenetic analysis of Papilio macilentus Janson, 1877 (Lepidoptera: Papilionoidea: Papilionidae)

open access: yesMitochondrial DNA. Part B. Resources
In the present study, the complete mitochondrial genome (mitogenome) of the Papilio macilentus (Lepidoptera: Papilionoidea: Papilionidae) was sequenced by next-generation sequencing method. The mitochondrial genome is a circular DNA molecule of 15,264 bp
Yun-Fei Wu   +5 more
doaj   +1 more source

The complete mitochondrial DNA sequence of Mongolian grayling Thymallus brevirostris

open access: yesMitochondrial DNA. Part B. Resources, 2019
Thymallus brevirostris is a specific grayling species that naturally occurs in Mongolia and Russia in Asia. The complete mitochondrial genome of the Mongolian grayling T.
Yao-Yao Li   +4 more
doaj   +1 more source

A new type of IRES within gag coding region recruits three initiation complexes on HIV-2 genomic RNA

open access: yesNucleic Acids Research, 2009
Genomic RNA of primate lentiviruses serves both as an mRNA that encodes Gag and Gag-Pol polyproteins and as a propagated genome. Translation of this RNA is initiated by standard cap dependant mechanism or by internal entry of the ribosome. Two regions of
L. Weill   +6 more
semanticscholar   +1 more source

Circulating tumor DNA monitoring and blood tumor mutational burden in patients with metastatic solid tumors treated with atezolizumab

open access: yesMolecular Oncology, EarlyView.
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton   +17 more
wiley   +1 more source

Complete sequence of the Tibetan Mastiff mitochondrial genome and its phylogenetic relationship with other Canids (Canis, Canidae)

open access: yesAnimal, 2011
In this study, the complete sequence of the Tibetan Mastiff mitochondrial genome (mtDNA) was determined, and the phylogenetic relationships between the Tibetan Mastiff and other species of Canidae were analyzed using the coyote (Canis latrans) as an ...
Yinxia Li   +4 more
doaj  

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