Results 171 to 180 of about 1,607,083 (320)

Allele-Specific Knockdown of Mutant Huntingtin Protein via Editing at Coding Region Single Nucleotide Polymorphism Heterozygosities. [PDF]

Hum Gene Ther, 2022
Oikemus SR, Pfister EL, Sapp E, Chase KO, Kennington LA, Hudgens E, Miller R, Zhu LJ, Chaudhary A, Mick EO, Sena-Esteves M, Wolfe SA, DiFiglia M, Aronin N, Brodsky MH.   +14 more
europepmc   +1 more source

Functions of the Heterologous Intron-Derived Fragments Intra and Extra Factor IX-cDNA Coding Region on the Human Factor IX Expression in HepG2 and Hek-293T Cells [PDF]

, 2018
Mohammad Reza Sam, Alireza Zomorodipour, Aliakbar Haddad‐Mashadrizeh, Mahdi Ghorbani, Gholam Ali Kardar, Sohrab Sam   +5 more
openalex   +1 more source

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source

Molecular characterization of Infectious Bursal Disease Virus isolated in Chile reveals several mutations in VP2 coding region and a reassortment in its genome. [PDF]

Vet Res Commun, 2022
Guzmán M, Cádiz L, Guerrero-Moncayo A, Cáceres F, Vidal S, Lapierre L, Sáenz L, Hidalgo H.   +7 more
europepmc   +1 more source

OR22 HLA-G regulatory and coding region haplotypes in papillary thyroid carcinoma

, 2018
Bruna C. Bertol, Guilherme Debortoli, Fabrício C. Dias, Jéssica Nayara Góes de Araújo, Nathalie L. de Figueiredo-Feitosa, Vivian Nogueira Silbiger, Celso Teixeira Mendes‐Junior, Erick C. Castelli, Léa Maria Zanini Maciel, Eduardo Antônio Donadi   +9 more
openalex   +2 more sources

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Polymorphisms of KLF3 gene coding region and identification of their functionality for abdominal fat in chickens. [PDF]

Vet Med Sci, 2021
Wang W, Li Y, Li Z, Wang N, Xiao F, Gao H, Guo H, Li H, Wang S.   +8 more
europepmc   +1 more source

Mitochondrial coding and control region variants are associated with Type-2 Diabetes in Pakistani population [PDF]

Saad Farooq, Syed Faizan-ul-Hasan Naqvi, Shahid Muhammad, Agnieszka Piotrowska-Nowaka, Syed Ali Raza Shah Bukhari, Ahsan Javed, Muhammad Irfan, Ishtiaq Ahmad Khan   +7 more
openalex   +1 more source

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source

G-Quadruplex Formation in a Putative Coding Region of White Spot Syndrome Virus: Structural and Thermodynamic Aspects. [PDF]

Chembiochem, 2021
Vianney YM, Purwanto MGM, Weisz K.
europepmc   +1 more source