Results 191 to 200 of about 7,506,861 (344)

Simulation‐free workflow for lattice radiation therapy using deep learning predicted synthetic computed tomography: A feasibility study

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose Lattice radiation therapy (LRT) is a form of spatially fractionated radiation therapy that allows increased total dose delivery aiming for improved treatment response without an increase in toxicities, commonly utilized for palliation of bulky tumors.
Libing Zhu   +9 more
wiley   +1 more source

A Novel CHMP2B Splicing Variant in Atypical Presentation of Familial Frontotemporal Lobar Degeneration

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT C‐truncating variants in the charged multivesicular body protein 2B (CHMP2B) gene are a rare cause of frontotemporal lobar degeneration (FTLD), previously identified only in Denmark, Belgium, and China. We report a novel CHMP2B splice‐site variant (c.35‐1G>A) associated with familial FTLD in Spain. The cases were two monozygotic male twins who
Sara Rubio‐Guerra   +17 more
wiley   +1 more source

Natural variations in the non-coding region of ZmNAC080308 contributes maintaining grain yield under drought stress in maize. [PDF]

open access: yesBMC Plant Biol, 2021
Wang N   +15 more
europepmc   +1 more source

Precision‐Optimised Post‐Stroke Prognoses

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Current medicine cannot confidently predict who will recover from post‐stroke impairments. Researchers have sought to bridge this gap by treating the post‐stroke prognostic problem as a machine learning problem, reporting prediction error metrics across samples of patients whose outcomes are known.
Thomas M. H. Hope   +4 more
wiley   +1 more source

Identification and functional characterization of new missense SNPs in the coding region of the TP53 gene. [PDF]

open access: yesCell Death Differ, 2021
Doffe F   +13 more
europepmc   +1 more source

Translating Muscle RNAseq Into the Clinic for the Diagnosis of Muscle Diseases

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Approximately half of patients with hereditary myopathies remain without a definitive genetic diagnosis after DNA next‐generation sequencing (NGS). Here, we implemented transcriptome analysis of muscle biopsies as a complementary diagnostic tool for patients with muscle disease but no definitive genetic diagnosis after exome ...
Alba Segarra‐Casas   +24 more
wiley   +1 more source

Helicobacter pylori induces mitochondrial DNA mutation and reactive oxygen species level in AGS cells

open access: yesInternational Journal of Medical Sciences, 2011
To investigate the role of ROS in the helicobacter pylori (Hp) induced mtDNA mutations, AGS cells were treated by extracts of Hp11638 or Hp11638M. The ROS levels, cytochrome C reductions, and intracellular ATP levels were measured.
Xue-Wen Huang, Rui-Hua Luo, Qi Zhao, Zhong-Ze Shen, Li-Li Huang, Xian-Yuan An, Lan-Jing Zhao, Jie Wang, Yu-Zheng Huang
doaj  

Detection of novel transcripts in the human mitochondrial DNA region coding for ATPase8—ATPase6 subunits [PDF]

open access: bronze, 1994
Maria Nardelli   +8 more
openalex   +1 more source

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