Results 191 to 200 of about 734,305 (335)
Code et données pour les sciences sociales (1) Introduction
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BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru +6 more
wiley +1 more source
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
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Assessing the Saudi Ministry of Health Instagram messaging through the lens of the health belief model. [PDF]
AlDossary S, Alzaid M, Albedewi H.
europepmc +1 more source
Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
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Exploring the Experiences of Individuals With Type 2 Diabetes in the Context of Alcohol Use and Lifestyle Change: A Phenomenological Study. [PDF]
Mantzouka C.
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ABSTRACT Background Poststroke fatigue (PSF) and frailty share substantial overlap in their manifestations, yet previous research has yielded conflicting results due to the use of heterogeneous frailty assessment tools. Objective To evaluate the independent impact of frailty on PSF using a unified measurement system (Tilburg Frailty Indicator, TFI ...
Chuan‐Bang Chen +6 more
wiley +1 more source
Exploring barriers to mental health care access among rural adolescents in Gondar Zuria, Ethiopia: a qualitative study. [PDF]
Mengesha AK +5 more
europepmc +1 more source
L’accessibilité croissante des ressources numérisées permet d’envisager de nouveaux moyens de production de la recherche en sciences humaines et sociales. A partir d’une recherche prosopographique de science politique portant sur les directeurs et directrices d’administrations centrales, qui occupent les postes de direction des ministères, cet article ...
Bina, Nicolas, Gramaize, Léopold
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