Results 71 to 80 of about 1,037,008 (337)

A cellular system to study responses to a collision between the transcription complex and a protein‐bound nick in the DNA template

FEBS Letters, EarlyView.
We present the cellular transcription‐coupled Flp‐nick system allowing the introduction of a Top1‐mimicking cleavage complex (Flpcc) at a Flp recognition target site within a controllable LacZ gene. LacZ transcription leads to the collision of RNA polymerase II (RNAPII) with Flpcc, and this causes RNAPII stalling, ubiquitination, and degradation.
Petra Herring, Morten Roedgaard, Camilla Myrup Holst, Helene Christensen, Birgitta R. Knudsen, Lotte Bjergbaek, Anni Hangaard Andersen   +6 more
wiley   +1 more source

Interoceptive inference, emotion, and the embodied self [PDF]

, 2013
The concept of the brain as a prediction machine has enjoyed a resurgence in the context of the Bayesian brain and predictive coding approaches within cognitive science.
Adams, Adams, Allman, Allman, Anil K. Seth, Apps, Armel, Aspell, Barnsley, Blanke, Blanke, Botvinick, Cantril, Cechetto, Clark, Clark, Craig, Craig, Craig, Critchley, Critchley, Critchley, Damasio, Damasio, Damasio, Dayan, Deen, Dolan, Egner, Ehrsson, Ernst, Evrard, Ferri, Fletcher, Friston, Friston, Friston, Friston, Friston, Frith, Frith, Garfinkel, Gendron, Gray, Gu, Harrison, Hinton, Hohwy, Holle, James, Kammers, Karnath, Keller, Khalsa, Kim, Lane, Lee, Lenggenhager, Lovero, Makin, Medford, Menon, Metzinger, Moseley, Northoff, Palaniyappan, Paulus, Phillips, Ploghaus, Preuschoff, Rohde, Schachter, Schandry, Seeley, Seth, Seth, Seymour, Sforza, Sierra, Silani, Singer, Singer, Suzuki, Synofzik, Tajadura-Jimenez, Tajadura-Jimenez, Tsakiris, Valins, Wolpert, Xiang, Young   +90 more
core   +1 more source

On the Origins of Bias in NLP through the Lens of the Jim Code [PDF]

arXiv, 2023
In this paper, we trace the biases in current natural language processing (NLP) models back to their origins in racism, sexism, and homophobia over the last 500 years. We review literature from critical race theory, gender studies, data ethics, and digital humanities studies, and summarize the origins of bias in NLP models from these social science ...
arxiv  

Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation

FEBS Letters, EarlyView.
Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley   +1 more source

Strategies for Improving Semi-automated Topic Classification of Media and Parliamentary documents [PDF]

, 2009
Since 1995 the techniques and capacities to store new electronic data and to make it available to many persons have become a common good. As of then, different organizations, such as research institutes, universities, libraries, and private companies ...
Atteveldt, W., van, Breeman, G.E., Kleinnijenhuis, J., Then, H., Timmermans, A.   +4 more
core   +1 more source

Of impacts, agents, and functions: An interdisciplinary meta-review of smart home energy management systems research [PDF]

, 2020
Smart home energy management technologies (SHEMS) have long been viewed as a promising opportunity to manage the way households use energy. Research on this topic has emerged across a variety of disciplines, focusing on different pieces of the SHEMS ...
McIlvennie, C, Pritoni, M, Sanguinetti, A   +2 more
core  

Connecting key competencies and social inquiry in primary social studies pedagogy: initial teacher education students' planning decisions and reflections. [PDF]

, 2010
Over 2007-2009 we have worked with the national curriculum's key competencies to establish their place and purpose in the social sciences learning area.
Hunter, Philippa Anne, Keown, Paul Ashley, Wynyard, Jill   +2 more
core   +2 more sources

From Spin States to Socially Integrated Ising Models: Proposed Applications of Graph States, Stabilizer States, Toric States to Opinion Dynamics [PDF]

arXiv, 2023
Recent research has developed the Ising model from physics, especially statistical mechanics, and it plays an important role in quantum computing, especially quantum annealing and quantum Monte Carlo methods. The model has also been used in opinion dynamics as a powerful tool for simulating social interactions and opinion formation processes ...
arxiv  

A stepwise emergence of evolution in the RNA world

FEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

Comprehensive and Clear: A Review of H. Russell Bernard and G.W. Ryan\u27s Analyzing Qualitative Data: Systematic Approaches [PDF]

, 2010
In their book Analyzing Qualitative Data: Systematic Approaches, Bernard and Ryan (2010) present a thorough review of qualitative data analysis. Main topic areas include data collection, coding, development of themes, qualitative analysis of words and ...
Victor, Shelley
core   +1 more source