Results 71 to 80 of about 741,973 (309)

Dialogue as Data in Learning Analytics for Productive Educational Dialogue [PDF]

, 2015
This paper provides a novel, conceptually driven stance on the state of the contemporary analytic challenges faced in the treatment of dialogue as a form of data across on- and offline sites of learning.
Knight, Simon, Littleton, Karen
core   +2 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

The Phenomenon of Bullying in Schools as a Basis for Developing Social Studies Learning Materials

Qalamuna
This qualitative research aims to analyze the phenomenon of bullying in schools to develop social sciences learning materials using literature studies and thematic synthesis.
Ares Faujian, Anik Widiastuti, Sudrajat Sudrajat   +2 more
doaj   +1 more source

Social Responsibility Over Academic Freedom: Emphasizing Ethics and Codes of Conduct Geared for a Scholar’s Duties Towards Science, Society and the Education System in Twenty-First Century Science

SSRN Electronic Journal, 2023
This paper explores the twin issues of Academic Freedom and Social Responsibility among researchers and scholars, and gaps in theory and praxis as well. It also discusses the current application of ethics and objectivity in science, and discusses the need for change so as to highlight a scholar’s duties towards science, society and the education system.
openaire   +1 more source

Datasets, sample descriptions and codes from Building bridges between natural and social science disciplines: a standardized methodology to combine data on ecosystem quality trends

, 2022
Despite a growing interest in interdisciplinary research, systematic ways of how to integrate data from different disciplines are still scarce. We argue that successful resource management relies on two key data sources: natural science data, which represents ecosystem structure and processes, and social science data, which describes people's ...
Richter, I., Roberts, B. R., Sailley, S. F., Sullivan, E., Cheung, V. V., Eales, J., Fortnam, M., Jontila, J. B., Maharja, C., Nguyen, T. Ha., Pahl, S., Praptiwi, R. A., Sugardjito, J., Sumeldan, J. D. C., Syazwan, W. M., Then, A. Y., Austen, M. C.   +16 more
openaire   +1 more source

Online discussion compensates for suboptimal timing of supportive information presentation in a digitally supported learning environment [PDF]

, 2012
This study used a sequential set-up to investigate the consecutive effects of timing of supportive information presentation (information before vs. information during the learning task clusters) in interactive digital learning materials (IDLMs) and type ...
Biemans, H.J.A., Busstra, M.C., Chizari, M., Geelen, A., Mulder, M., Noroozi, O., Tobi, H., Veer, P., van 't   +7 more
core   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

The experiences of medical and pharmacy students participating in a collaborative online international learning on social accountability and global health: a qualitative study

BMC Medical Education
Background Social accountability aims to promote a collective ethic that upholds the fundamental values of equity, efficiency, solidarity, and social justice in healthcare and is now considered as a critical mission of academic health centers ...
Anne-Emmanuelle Rault, Janie Giard, Joël Ladner, Offoue Kra, Raphaël Randrianarivo, Marceau Chenault, Edouard Leaune   +6 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source