Results 41 to 50 of about 6,175,868 (232)
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Equalization and Coding Techniques for Edge Modulation Signaling
IEEE Open Journal of Circuits and SystemsThis paper describes equalization, coding, and crosstalk reduction techniques for edge modulation signaling. We analyze the inter-symbol interference of edge modulation using enumeration method and present expressions for the error rate from inter-edge ...
Richelle L. Smith +4 more
doaj +1 more source
A Comparative Study of Speech Coding Techniques for Electro Larynx Speech Production
Iraqi Journal of Information & Communication Technology, 2022 Speech coding is a method of earning a tight speech signals representation for efficient storage and efficient transmission over band limited wired or wireless channels.
Zinah J. Mohammed +1 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Erasure Coding for Cloud Storage Systems: A Survey
Tsinghua Science and Technology, 2013 In the current era of cloud computing, data stored in the cloud is being generated at a tremendous speed, and thus the cloud storage system has become one of the key components in cloud computing.
Jun Li, Baochun Li
doaj +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
European Journal of Breast Health, 2020 Objective:This is a pilot study to assess whether a file-colour-coded triage navigation system for patients on primary chemotherapy improves compliance and adherence and if it decreases defaulting.Materials and Methods:All breast cancer patients are ...
Carol Ann Benn +6 more
doaj +1 more source