Results 81 to 90 of about 6,175,868 (232)

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

open access: yesMolecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee   +3 more
wiley   +1 more source

Advances in predictive wavelet transform image coding [PDF]

open access: yes
In this work, it is shown that a fractal image coding can be placed in a conventional predictive framework by using a wavelet representation. This has the significant advantage of simplifying decoding by avoiding iteration and of relating the technique ...
Levy, Ian Karl, Wilson, Roland
core  

Performance analysis for network coding using ant colony routing [PDF]

open access: yes, 2011
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.The aim of this thesis is to conduct performance investigation of a combined system of Network Coding (NC) technique with Ant-Colony (ACO) routing protocol.
Sabri, Dalia
core   +4 more sources

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Ambiguity Suppression by Azimuth Phase Coding in Multichannel SAR Systems [PDF]

open access: yes, 2011
The Azimuth Phase Coding (APC) technique, proposed to suppress range ambiguities in conventional SAR systems, stands out for its low implementation complexity and its effectiveness for point and distributed ambiguities.
Bordoni, Federica   +5 more
core   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

An efficient very low bit rate video coding scheme using warping prediction and wavelet-based residual coding

open access: yes, 2022
S.21-24This paper describes a video coding algorithm that combines new ideas in motion estimation and wavelet-based coding techniques. A motion estimation technique using an image warping model is employed to reduce temporal redundancies in a given image
Marpe, D., Heising, G., Cycon, H.L.
core   +1 more source

Behaviour Change Techniques embedded in health and lifestyle apps: coding and analysis.

open access: yesFrontiers in Public Health, 2015
Background There is evidence showing that commercially available health and lifestyle apps can be used as co-adjuvants to clinical interventions and for the prevention of chronic and non-communicable diseases.
Gaston Antezana
doaj   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

open access: yesMolecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim   +11 more
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

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