Results 161 to 170 of about 115,610 (302)

Discharge Coefficient Measurements of Film-Cooling Holes With Expanded Exits,”

open access: yes, 1998
This paper presents the discharge coefficients of three film-cooling hole geometries tested over a wide range of flow conditions. The hole geometries include a cylindrical hole and two holes with a diffuser shaped exit portion (i.e.
A Schulz, S Wittig, M Gritsch
core  

Amuc_1473 Links Gut Microbes to Skeletal Homeostasis and Counteracts Multifactorial Osteoporosis

open access: yesAdvanced Science, EarlyView.
Amuc_1473, a previously uncharacterized protein enriched in Akkermansia muciniphila‐derived extracellular vesicles, is identified as a gut–bone messenger that promotes osteogenesis and inhibits osteoclastogenesis by engaging transcriptional and translational regulators in bone cells.
Shan‐Shan Rao   +28 more
wiley   +1 more source

Astrocytic Phenotypic Switching in Posterior Piriform Cortex Orchestrates Bone Cancer Pain–Depression Comorbidity via Purinergic–Noradrenergic Signaling

open access: yesAdvanced Science, EarlyView.
Bone cancer pain and depression share a common origin: astrocytic A2‐to‐A1 transition in the posterior piriform cortex. This phenotypic shift disrupts the ATP–adenosine–A2AR–norepinephrine axis, simultaneously driving nociceptive and affective dysfunction.
Jiang‐Ping Liu   +14 more
wiley   +1 more source

Predictive factors for functional outcomes in patients receiving total knee arthroplasty. [PDF]

open access: yesMedicine (Baltimore)
Lai WW   +5 more
europepmc   +1 more source

Analysis of influence of the relative weir height of rectangular broad-crested weir on discharge coefficient

open access: yes, 2013
This diploma thesis dealt with the influence of relative weir height of rectangular broad-crested weir on discharge coefficient. Based on the level measurement in front of weir for different heights of the weir P and discharges were determined values of ...
Knéblová, Michaela
core  

TME/NIR Dual‐Responsive Zinc‐Based Targeted Nanoagonist for Multimodal Amplification of STING‐Mediated Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
A multifunctional nanoagonist (cDZ@IP) enables nano‐metabolite–driven multimodal activation of the STING pathway and enhanced immune recognition, achieving potent antitumor immunity and suppressing tumor growth and metastasis. This strategy highlights the rational design of therapeutic metabolites and establishes a new paradigm bridging nanomedicine ...
Kepeng Hu   +17 more
wiley   +1 more source

Cognitive Functioning After Circulatory Shock: A Prospective Observational Study. [PDF]

open access: yesActa Anaesthesiol Scand
Laurila S   +13 more
europepmc   +1 more source

Cross‐Modal Denoising and Integration of Spatial Multi‐Omics Data with CANDIES

open access: yesAdvanced Science, EarlyView.
In this paper, we introduce CANDIES, which leverages a conditional diffusion model and contrastive learning to effectively denoise and integrate spatial multi‐omics data. We conduct extensive evaluations on diverse synthetic and real datasets, CANDIES shows superior performance on various downstream tasks, including denoising, spatial domain ...
Ye Liu   +5 more
wiley   +1 more source

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