Results 171 to 180 of about 2,005,242 (383)
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine+10 more
wiley +1 more source
Cognition On The Bleeding From Internal Carotid Artery In The Petrous Pyramid
Takashi Takahara
openalex +2 more sources
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop+10 more
wiley +1 more source
Cohabitation: Computation at 70, Cognition at 20 [PDF]
Zenon Pylyshyn cast cognition's lot with computation, stretching the Church/Turing Thesis to its limit: We had no idea how the mind did anything, whereas we knew computation could do just about everything. Doing it with images would be like doing it with
Harnad, Stevan
core
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed+8 more
wiley +1 more source
Distributed Processes, Distributed Cognizers and Collaborative Cognition
Cognition is thinking; it feels like something to think, and only those who can feel can think. There are also things that thinkers can do. We know neither how thinkers can think nor how they are able do what they can do.
Harnad, Stevan
core
Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho+11 more
wiley +1 more source