Results 171 to 180 of about 814,206 (314)

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Correction: Are Glucagon-Like Peptide‑1 (GLP-1) Receptor Agonists Central Nervous System (CNS) Penetrant: A Narrative Review

Neurology and Therapy
Juliana West, Maggie Li, Sabrina Wong, Gia Han Le, Kayla M. Teopiz, Kyle Valentino, Christine E. Dri, Roger S. McIntyre   +7 more
doaj   +1 more source

A case-control study examining the relationship between social cognition and post-traumatic stress disorder. [PDF]

BJPsych Open
Wiseman CE, Lawrence AD, Bisson JI, Bader M, Zammit S.   +4 more
europepmc   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Mapping behavioural mechanisms linking childhood maltreatment, cognition, impulsivity, and suicidality in bipolar disorder: A network approach. [PDF]

Transl Psychiatry
Fares-Otero NE, Iversen AE, Gutiérrez-Zotes A, Zarp J, Jiménez E, Sánchez-Moreno J, Pomarol-Clotet E, Vieta E, Kjærstad HL, Vilella E, Miskowiak KW.   +10 more
europepmc   +1 more source

The need for cognition and the curse of cognition [PDF]

Diagnosis, 2018
openaire   +2 more sources

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Resituating cognition [PDF]

, 2010
Arthur Glenberg, Peter R. Killeen, Peter Killeen, Arthur M. Glenberg   +3 more
core   +1 more source

Diagnostic test accuracies of 4AT items are consistent across the range of baseline cognition: results from two prospective studies. [PDF]

Age Ageing
Hogan P, Cheston H, Dunne O, Gardner D, McWhirter A, Rawle MJ, Stoodley I, Richardson SJ, Allan LM, MacLullich AMJ, Davis DHJ, Tsui A.   +11 more
europepmc   +1 more source