Microglial MS4A4A Protects against Epileptic Seizures in Alzheimer's Disease
This study has unveiled significant new insights into the role of MS4A4A in Alzheimer's disease‐related epilepsy, highlighting its impact on microglial phagocytosis, mitochondrial metabolism, and cytoskeleton, and demonstrating its therapeutic potential in epilepsy management.
Meng Jiang+10 more
wiley +1 more source
[Do cognitive-behavioral group therapies in the treatment of anxiety disorders have an advantage over individual treatments?]. [PDF]
Valentino Pomini
openalex +1 more source
Generation of Neural Organoids and Their Application in Disease Modeling and Regenerative Medicine
Neural organoids provide a versatile platform for neurological research. Advances in organoid technology have partially achieved human neural tissue complexity in terms of tissue structure, cell diversity, and neural signaling, offering insights into neural disorders and regenerative strategies. Technology advances from biomaterials, bio‐manufacturing,
Ruiqi Huang+4 more
wiley +1 more source
Managing stress at workplace using rational emotive behavioral therapy (REBT) approach [PDF]
This paper discusses how the Rational Emotive Behavioral Therapy (REBT) approach can be applied on employees at workplace to manage their stress. Rational-Emotive Behavior Therapy (REBT) is a useful cognitive-behavioral approach in understanding the ...
Amat Senin, Aslan, Mahfar, Mastura
core
Background: Cognitive behavioral therapy is the first-line and golden standard in treating chronic insomnia disorder but some studies showed that by addressing metacognitive components, its efficacy increases. The present study aimed to evaluate efficacy
Behzad Salmani * +4 more
doaj
Are Large Language Models Possible to Conduct Cognitive Behavioral Therapy? [PDF]
In contemporary society, the issue of psychological health has become increasingly prominent, characterized by the diversification, complexity, and universality of mental disorders. Cognitive Behavioral Therapy (CBT), currently the most influential and clinically effective psychological treatment method with no side effects, has limited coverage and ...
arxiv
Cognitive‐behavioral group therapy versus phenelzine in social phobia: Long term outcome
Michael R. Liebowitz+11 more
openalex +1 more source
On the learning curve: the emerging evidence supporting cognitive–behavioral therapies for adolescent substance abuse [PDF]
Holly Barrett Waldron, Yifrah Kaminer
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Activation of Kir4.1 Channels by 2‐D08 Promotes Myelin Repair in Multiple Sclerosis
Multiple sclerosis causes myelin loss and neurological dysfunction. This study shows that 2‐D08, a small molecule targeting Kir4.1 channels, promotes OPCs differentiation via FYN tyrosine kinase phosphorylation and the FYN/MYRF pathway. It significantly improves myelin repair and motor deficits in EAE mice and marmosets, highlighting its potential as a
Mingdong Liu+17 more
wiley +1 more source