Results 31 to 40 of about 238,257 (266)

Diffusion Spectrum Imaging Maps Early Axonal Loss and a Unique Progressive Signal in Neuronal Intranuclear Inclusion Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang, Yixiu Pei, Xiaobao Hu, Ying Xiong, Fang Wang, Yanyan Yu, Min Zhu, Dandan Tan, Meihong Zhou, Daojun Hong, Fuqing Zhou   +10 more
wiley   +1 more source

Are Changes in Worry Associated with Treatment Response in Cognitive Behavioral Therapy for Insomnia?

, 2014
Aim: Little is known about why some patients respond to cognitive behavioral therapy for insomnia, whereas other patients do not. To understand differences in treatment response, there is a dire need to examine processes of change.
Sunnhed, Rikard,, Jansson-Fröjmark, Markus,   +1 more
core   +1 more source

Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi, Caroline Gochanour, Seung Ho Choi, Hyunkeun Cho, Chelsea Caspell‐Garcia, Christopher Coffey, Michael Brumm, David‐Erick Lafontant, Yuge Xiao, Thomas Tropea, John Seibyl, Caroline Tanner, Charles S. Venuto, Karl Kieburtz, Lana M. Chahine, Kathleen L. Poston, Andrew Siderowf, Kenneth Marek, Tanya Simuni, The Parkinson's Progression Markers Initiative   +19 more
wiley   +1 more source

The Beck Initiative : training school-based mental health staff in cognitive therapy [PDF]

, 2013
A growing literature supports cognitive therapy (CT) as an efficacious treatment for youth struggling with emotional or behavioral problems. Recently, work in this area has extended the dissemination of CT to school-based settings.
Hurford, Matthew O., Evans, Arthur, Shari Jager-Hyman, Arthur Evans, Betsy Feinberg, Matthew O. Hurford, Feinberg, Betsy, Kristin Pontoski, Creed, Torrey A., Zachary Rosenberg, Torrey A. Creed, Aaron T. Beck, Pontoski, Kristin, Rosenberg, Zachary, Jager-Hyman, Shari, Beck, Aaron T.   +15 more
core  

Protocol for the saMS trial (supportive adjustment for multiple sclerosis): a randomized controlled trial comparing cognitive behavioral therapy to supportive listening for adjustment to multiple sclerosis

, 2009
BackgroundMultiple Sclerosis (MS) is an incurable, chronic, potentially progressive and unpredictable disease of the central nervous system. The disease produces a range of unpleasant and debilitating symptoms, which can have a profound impact including ...
McCrone Paul, Roche Suzanne, Dennison Laura, Sabine Landau, Moss-Morris, Rona, Trudie Chalder, Chalder, Trudie, Moss-Morris Rona, Lucy Yardley, Chalder Trudie, Roche, Suzanne, Yardley, Lucy, Suzanne Roche, McCrone, Paul, Yardley Lucy, Landau, Sabine; id_orcid, Chalder, Trudie; id_orcid, Landau, Sabine, Laura Dennison, Dennison, Laura, Paul McCrone, Landau Sabine, Rona Moss-Morris   +22 more
core   +1 more source

Beyond dopamine: functional MRI predictors of responsiveness to cognitive behaviour therapy for psychosis [PDF]

, 2010
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Johns, LC, Dominic Fannon, Kuipers, Elizabeth; id_orcid, Dominic H Ffytche, Peters, Emmanuelle R; id_orcid, McGuire, PA, Kumari, V, Preethi Premkumar, Antonova, E, Elizabeth Kuipers, Williams, SRC, McGuire, Philip A, Williams, SCR, Philip A McGuire, Raveendran, Vinodkumar, Elena Antonova, Premkumar, P, McGuire, PK, Louise C Johns, Kuipers, E, Johns, Louise C, Peters, ER, Ffytche, DH, Veena Kumari, Raveendran, V, Fannon, D, Andrew, Christopher, Steven C R Williams, Kumari, Veena, Ffytche, Dominic H, Emmanuelle R Peters, Antonova, Elena; id_orcid, Vinodkumar Raveendran, Christopher Andrew, Williams, Steven C.R.; id_orcid, Andrew, C, Fannon, Dominic, Premkumar, Preethi   +37 more
core   +1 more source

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende, Emilien Petit, Young Woo Park, Sophie Tezenas du Montcel, James M. Joers, Jonathan M. DuBois, H. Moore Arnold, Michal Povazan, Ipek Özdemir, Guita Banan, Romain Valabregue, Philipp Ehses, Jennifer Faber, Chiadi U. Onyike, Peter B. Barker, Jeremy D. Schmahmann, Eva‐Maria Ratai, Sub H. Subramony, Thomas H. Mareci, Khalaf O. Bushara, Henry Paulson, Thomas Klockgether, Alexandra Durr, Tetsuo Ashizawa, Christophe Lenglet, Gülin Öz, READISCA Investigators   +26 more
wiley   +1 more source

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher, Charles B. Malpas, Stuart J. McDonald, William T. O’Brien, Craig Despott, Kelly L. Bertram, Matthew P. Pase, Lukas Frontzkowski, Meng Law, Terence J. O’Brien, Lucy Vivash   +10 more
wiley   +1 more source

Cognitive-behavioral therapy for HIV medication adherence and depression

, 2004
For patients with HIV, depression is a common, distressing condition that can interfere with a critical self-care behavior — adherence to antiretroviral therapy. The present study describes a cognitive-behavioral treatment designed to integrate cognitive-
Hendriksen, Ellen S, Safren, Steven A, Otto, Michael W, Mayer, Kenneth H, Pickard, Robert, Mimiaga, Matthew J   +5 more
core   +1 more source

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett, Abigail Dubois, Melanie Leguizamon, Alexander Song, Paula Trujillo, Colin D. McKnight, Ciaran M. Considine, Manus J. Donahue, Daniel O. Claassen   +8 more
wiley   +1 more source