Results 61 to 70 of about 590,203 (332)
Genetic Diversity and Expanded Phenotypes in Dystonia: Insights From Large‐Scale Exome Sequencing
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Dystonia is one of the most prevalent movement disorders, characterized by significant clinical and etiological heterogeneity. Despite considerable heritability (~25%), the etiology in most patients remains elusive. Moreover, understanding correlations between clinical manifestations and genetic variants has become increasingly ...
Mirja Thomsen +47 more
wiley +1 more source
Stage‐Dependent Inhibitory Connectivity in Striatal‐Motor Circuit in Huntington's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Elucidating dysfunctional connectivity patterns among key brain regions in Huntington's disease (HD) underlying progression may have implications for developing treatment and therapeutic evaluation. Objective Explore the relationship between abnormal spontaneous resting‐state activity and atrophy in HD‐specific brain regions and ...
Yinghua Jing +4 more
wiley +1 more source
Analysis of rolling group therapy data using conditionally autoregressive priors [PDF]
, 2011 Group therapy is a central treatment modality for behavioral health disorders such as alcohol and other drug use (AOD) and depression. Group therapy is often delivered under a rolling (or open) admissions policy, where new clients are continuously ...
Daniel F. Mccaffrey +4 more
core +1 more source
BCS1L‐Associated Disease: 5′‐UTR Variant Shifts the Phenotype Towards Axonal Neuropathy
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives To investigate the consequences of a pathogenic missense variant (c.838C>T; p.L280F) and a 5′‐UTR regulatory variant (c.‐122G>T) in BCS1L on disease pathogenesis and to understand how regulatory variants influence disease severity and clinical presentation.
Rotem Orbach +11 more
wiley +1 more source
Neuropsychiatric Disease and Treatment, 2016 Issei Shinmei,1,2 Kei Kobayashi,3 Yuki Oe,1 Yuriko Takagishi,1,4 Ayako Kanie,1 Masaya Ito,1 Yoshitake Takebayashi,1,5 Miho Murata,3 Masaru Horikoshi,1 Roseanne D Dobkin6 1National Center for Cognitive Behavioral Therapy and Research, National Center of ...
Shinmei I +9 more
doaj
Adolescent stealing treated with motivational interviewing and imaginal desensitization — Case report [PDF]
, 2012 Background: Adolescent shoplifting occurs in an estimated 15% of the United States population. Although adolescent stealing is associated with significant psychosocial consequences there is limited research concerning efficacious treatments. Case
Donahue, Christopher B. +2 more
core +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective The Apolipoprotein (APOE) ε4 allele is the strongest genetic risk factor for late‐onset Alzheimer's disease (AD); however, many ε4 carriers remain cognitively intact into old age. Leveraging plasma neuron‐derived extracellular vesicles (NDEVs), we sought to identify biomarkers of cognitive resilience and their interplay with APOE ...
Apostolos Manolopoulos +17 more
wiley +1 more source
مجله علوم روانشناختی, 2020 Background: Several studies have been conducted on the impact of acceptance-based and cognitive-behavioral therapy. But research comparing the efficacy of acceptance-based and commitment-based therapy and positive cognitive-behavioral therapy on pain ...
Siavash Kiani +4 more
doaj
Pengaruh dan Efektifitas Cognitive Behavioral Therapy (Cbt) Berbasis Komputer terhadap Klien Cemas dan Depresi [PDF]
, 2014 : Anxiety and Depression is a form of mental disorder that most commonly occurs. Care and effective treatment for anxiety disorders and depression are indispensable so that the disorder people may re-productive in meeting the needs of life, do not rely ...
Zakiyah, Z. (Zakiyah)
core
Development of an integrated cognitive behavioral therapy for anxiety and opioid use disorder: Study protocol and methods [PDF]
, 2017 Opioid use disorder is a highly disabling psychiatric disorder, and is associated with both significant functional disruption and risk for negative health outcomes such as infectious disease and fatal overdose. Even among those who receive evidence-based
Barlow, David H. +5 more
core +1 more source