Results 51 to 60 of about 4,029,695 (306)

Cognitive flexibility, OCD and the brain

open access: yesBrain, 2022
This scientific commentary refers to ‘Unbalanced fronto-pallidal neurocircuit underlying set shifting in obsessive-compulsive disorder’ by Kim et al. (https://doi.org/10.1093/brain/awab483).
openaire   +2 more sources

Disentangling the neural correlates of corticobasal syndrome and corticobasal degeneration with systematic and quantitative ALE meta-analyses

open access: yesnpj Parkinson's Disease, 2017
Differential diagnosis: imaging to tell the difference Brain imaging could be used to distinguish between patients with corticobasal degeneration (CBD) and Parkinson's disease (PD).
Franziska Albrecht   +4 more
doaj   +1 more source

Spatial decision dynamics during wayfinding: intersections prompt the decision-making process

open access: yesCognitive Research, 2018
Intersections are critical decision points for wayfinders, but it is unknown how decision dynamics unfold during pedestrian wayfinding. Some research implies that pedestrians leverage available visual cues to actively compare options while in an ...
Tad T. Brunyé   +3 more
doaj   +1 more source

Understanding the role of the CB1 toggle switch in interaction networks using molecular dynamics simulation

open access: yesScientific Reports, 2021
The cannabinoid receptor 1 (CB1) is a class A G-protein coupled receptor (GPCR) that can exert various effects on the human body through the endocannabinoid system. Understanding CB1 activation has many benefits for the medical use of cannabinoids.
Sangho Ji, Wonjin Yang, Wookyung Yu
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Alterations in functional connectivity in the salience network shared by depressive symptoms and smartphone overuse

open access: yesScientific Reports
Globally, the age when children start using smartphones has decreased. Concurrently, the increased use of smartphones among children in developmental stages has caused serious effects, such as depression.
Seonkyoung Lee   +4 more
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

ARTS, BRAIN AND COGNITION

open access: yesPsychiatria Danubina, 2017
Art is a product of human creativity; it is a superior skill that can be learned by study, practice and observation. Modern neuroscience and neuroimaging enable study of the processes during artistic performance. Creative people have less marked hemispheric dominance.
Demarin, Vida   +3 more
openaire   +5 more sources

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Cognitive control states and traits modulate lexical competition during word production

open access: yesScientific Reports
Word production often involves resolving competition between multiple activated word candidates. This study investigated how cognitive control states and traits modulate lexical competition during production, combining behavioral and fMRI techniques ...
Sifan Zhang   +5 more
doaj   +1 more source

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