Results 51 to 60 of about 3,770,702 (243)

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Cognitive Pathways to Belief in Karma and Belief in God [PDF]

, 2021
Supporting Information: Additional supporting information may be found online in the Supporting Information section at the end of the article: Appendix S1: Supplementary results at: https://onlinelibrary.wiley.com/action/downloadSupplement?doi=10.1111 ...
Norenzayan, A, Baimel, A, White, CJM, Willard, AK   +3 more
core   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Why it is important to build robots capable of doing science [PDF]

, 2002
Science, like any other cognitive activity, is grounded in the sensorimotor interaction of our bodies with the environment. Human embodiment thus constrains the class of scientific concepts and theories which are accessible to us.
Florian, Razvan V.
core  

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

The Relationship between Mental Workload and Job Satisfaction of Faculty Members with their Educational Performance [PDF]

Journal of Medical Education and Development
Introduction: Workload and job satisfaction are among the most influential factors affecting job performance. Therefore, this study aims to assess the cognitive workload and job satisfaction and their impact on the quality of education faculty members ...
Neda Mahdavi, Masoud Shafiee Motlagh2, Zahra Cheraghi, Hossein Jafari Mansoorian, Vajihe Ramazani Doroh, Leili tapak, Maryam Afshari, Amin Doosti-Irani   +7 more
doaj  

The pedagogy of rest: a theory-integrative narrative review of intentional pauses in education

Frontiers in Education
Modern schooling often confuses seriousness with prolonged visible exertion, speed, and continuous time-on-task. But cognitive, developmental, neurobiological, and occupational-health sciences have shown that learning relies on cyclical periods of effort
Rotimi Peter Oye
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Hierarchical motor competencies and academic achievement: visual-motor integration as the key correlate for school-age children in a disadvantaged context

Frontiers in Psychology
PurposeThe relationship between motor competencies and academic achievement in children from disadvantaged backgrounds remains unclear. This study proposes a theoretical framework titled “Motor Competency–Academic Achievement Link Based on Cognitive ...
Xue Li
doaj   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source