Results 211 to 220 of about 16,133,192 (317)

Potent Liver‐Tropic mRNA Lipid Nanoparticles: ApoE‐Mediated Delivery Through a Low‐Density Lipoprotein Receptor Independent Uptake Mechanism

Advanced Materials, EarlyView.
Helper and ionizable lipids play a crucial role in determining ApoE binding and subsequent liver tropism and LDLR‐mediated uptake. Ionizable lipids primarily govern the LDLR‐independent uptake pathway. This complementary interplay between lipid components ultimately governs LNP delivery performance and therapeutic efficacy in the liver.
Ashish Sarode, Christian Ortiz, Tadeh Derstepanian, Natalia Vargas‐Montoya, Priyal Patel, Nikita Khadse, Saikat Manna, Ryan Landis, Joseph Skaleski, Lianne Boeglin, Hongfeng Deng, Anusha Dias, Hong Wang, Debora Barreiros Petropolis, Barak Yahalom, Shrirang Karve, Frank DeRosa   +16 more
wiley   +1 more source

Associations of Dietary Decanoic Acid Intake With Cognitive Function in the Elderly and the Mediating Effects of Hypertension and Diabetes: An Analysis From NHANES 2011-2014. [PDF]

Brain Behav
Zhu H, Fu Q, Hu J, Wu Y, Min J.
europepmc   +1 more source

Recent Progress on Flexible Multimodal Sensors: Decoupling Strategies, Fabrication and Applications

Advanced Materials, EarlyView.
In this review, we establish a tripartite decoupling framework for flexible multimodal sensors, which elucidates the underlying principles of signal crosstalk and their solutions through material design, structural engineering, and AI algorithms. We also demonstrate its potential applications across environmental monitoring, health monitoring, human ...
Tao Wu, Yu‐Tao Li, Luyu Zhao, Yi Zhang, Zhaojie Zhang, Jian Yuan, Yiwen Wu, Anqi Che, Yuanxiao Ma, Yang Chai, Yeliang Wang   +10 more
wiley   +1 more source

Transcranial direct current stimulation and cognitive training in the treatment of cognitive deficit in schizophrenia: a randomized controlled trial. [PDF]

BMC Psychiatry
Stuchlíková Z, Biačková N, Laskov O, Čechová A, Böhmová NA, Renková V, Jelínková B, Novák T, Klírová M.   +8 more
europepmc   +1 more source

Respiratory Signal Processing and Analysis Using Flexible Capacitive Sensor Data

Advanced Materials Technologies, EarlyView.
Capacitive pressure sensors based on poly(glycerol sebacate) (PGS) substrates are developed for continuous, non‐invasive respiratory monitoring. Integrated with a signal processing algorithm, they enable accurate tracking of thoracic expansion and retraction.
Bernardo A. Vicente, Raquel Sebastião, Alda Marques, Vitor Sencadas   +3 more
wiley   +1 more source

Generative artificial intelligence heuristic cues, trust and continuous intention of CBeC platform and the moderating role of information overload. [PDF]

Sci Rep
Li X, Liu H, Zhou T, Hu C, Ramayah T.
europepmc   +1 more source

Engineered Microfluidic Organoid Systems: New Paradigms for Menopause Mechanism Research and Personalized Medicine

Advanced Materials Technologies, EarlyView.
This review explores the integration of microfluidic technology with organoid systems as an innovative platform for studying menopausea complex multi‐organ condition. By enabling precise simulation of inter‐organ communication and hormone responses, microfluidic organoids offer a physiologically relevant model for investigating menopausal syndrome and ...
Qianyi Zhang, He Huang, Hongliang Dong, Qiang Ma, Hongyan Jin   +4 more
wiley   +1 more source

Physical Activity, Cognitive Health and Learning in Youth: A Narrative Umbrella Review. [PDF]

Int J Environ Res Public Health
Unterguggenberger S.
europepmc   +1 more source