Results 111 to 120 of about 2,883,132 (337)

Abnormal gut microbiota composition contributes to cognitive dysfunction in SAMP8 mice

Aging, 2018
Alzheimer’s disease is characterized by cognitive dysfunction and aging is an important predisposing factor; however, the pathological and therapeutic mechanisms are not fully understood.
Gaofeng Zhan, Ning Yang, Shan Li, Nian-nian Huang, Xi Fang, Jie Zhang, Bin Zhu, Ling Yang, Chun Yang, A. Luo   +9 more
semanticscholar   +1 more source

Association between Serum GDF-15 and Cognitive Dysfunction in Hemodialysis Patients

Biomedicines
Cognitive dysfunction is more frequent in end-stage renal disease (ESRD) patients undergoing hemodialysis compared with the healthy population, emphasizing the need for early detection.
Hae Ri Kim, Moo Jun Kim, Jae Wan Jeon, Young Rok Ham, Ki Ryang Na, Hyerim Park, Jwa-Jin Kim, Dae Eun Choi   +7 more
doaj   +1 more source

The Diverse Neuromuscular Spectrum of VPS13A Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective VPS13A disease (chorea‐acanthocytosis) is a rare neurodegenerative disorder caused by biallelic variants in VPS13A, typically presenting with hyperkinetic movement disorders, while neuromuscular signs are often mild. The aim of the project was to investigate the frequency and severity of neuromuscular impairment in VPS13A disease ...
Anne Buchberger, Evamaria Riedel, Marie Hackenberg, Alexander Mensch, Stefanie Beck‐Woedl, Joohyun Park, Tobias B. Haack, Bernhard Haslinger, Jan Kirschke, Holger Prokisch, Andreas Hermann, Christian Mawrin, Adrian Danek, Benedikt Schoser, Kevin Peikert, Marcus Deschauer, Isabell Cordts   +16 more
wiley   +1 more source

The Relationship Between Cognitive Dysfunction and Symptom Dimensions Across Schizophrenia, Bipolar Disorder, and Major Depressive Disorder

Frontiers in Psychiatry, 2019
Background: Cognitive dysfunction is considered a core feature among schizophrenia (SZ), bipolar disorder (BD), and major depressive disorder (MDD).
Yue Zhu, F. Womer, Haixia Leng, Miao Chang, Zhiyang Yin, Yan-ge Wei, Qian Zhou, S. Fu, Xin Deng, Jing Lv, Yanzhuo Song, Yinzhu Ma, Xinyu Sun, Jing Bao, Shengnan Wei, Xiaowei Jiang, Shuping Tan, Yanqing Tang, Fei Wang   +18 more
semanticscholar   +1 more source

Lesion Location and Functional Connections Reveal Cognitive Impairment Networks in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive impairment, fatigue, and depression are common in multiple sclerosis (MS), potentially due to disruption of regional functional connectivity caused by white matter (WM) lesions. We explored whether WM lesions functionally connected to specific brain regions contribute to these MS‐related manifestations.
Alessandro Franceschini, Paolo Preziosa, Paola Valsasina, Damiano Mistri, Monica Margoni, Federica Esposito, Massimo Filippi, Maria A. Rocca   +7 more
wiley   +1 more source

Expanding Hereditary Spastic Paraplegias Limits: Biallelic SPAST Variants in Cerebral Palsy Mimics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegias (HSP) are rare neurodegenerative disorders marked by spasticity and lower limb weakness. The most common type, SPG4, is usually autosomal dominant and caused by SPAST gene variants, typically presenting as pure HSP.
Gregorio A. Nolasco, Mònica Roldán, Yalda Jamshidi, Ioannis Georvasilis, Rocío Jadraque Rodríguez, Reza Boostani, Ali Shoeibi, Lluís Armengol, Anna Codina, Ehsan Ghayoor Karimiani, Cristina Hernando‐Davalillo, Loreto Martorell, María Luisa Ramírez Almaraz, Jordi Muchart, Carlos Ortez, Andrés Nascimento, Roser Urreizti, Daniel Natera‐de Benito, Mercedes Serrano   +18 more
wiley   +1 more source

Post-operative cognitive dysfunction – A brief review

Journal of Medical and Scientific Research, 2016
Postoperative cognitive dysfunction (POCD) can be referred to as a mild but possibly long-lasting altered intellectual function occurring after surgery, which is more common in old age. It may last from a few hours to some months or may be permanent.
Patki J, Ravinutala S
doaj   +1 more source

Visual Masking: A Reliable Measure for the Assessment of Cognitive Dysfunction in the Elderly? [PDF]

, 1991
Thomas Schläpfer, Marina T. Groner, E. Lavoyer, Hans U. Fisch   +3 more
openalex   +1 more source

Enhancing myelin renewal reverses cognitive dysfunction in a murine model of Alzheimer’s disease

Neuron, 2021
Jing-Fei Chen, Kun Liu, Bo Hu, Ronghui Li, Wendy Xin, Hao Chen, Fei Wang, Lin Chen, Ruixue Li, S. Ren, L. Xiao, J. Chan, F. Mei   +12 more
semanticscholar   +1 more source

The Association Between Serum Uric Acid Levels and the Risk of Cognitive Dysfunction in Patients With Atrial Fibrillation

International Journal of Endocrinology
Patients with atrial fibrillation (AF) are linked to an increased risk of cognitive dysfunction, and serum uric acid levels play an important factor in cognitive dysfunction. However, the optimal serum uric acid level in patients with AF remains unclear.
Miaomiao Shang, Meijuan Wang, Qian Cui, Dongmei Song, Wenqing Wang, Jing Xue, Guomei Xu, Dandan Sun   +7 more
doaj   +1 more source