Results 131 to 140 of about 339,240 (318)
Evaluation and Treatment of Cognitive Dysfunctions in Schizophrenia and Bipolar Disorder
Psikiyatride Güncel YaklaşımlarCognitive dysfunction is the most important determinant for the recovery in schizophrenia and bipolar disorder. Cognitive dysfunction serves as an endophenotype although it may be a consequence of drug treatments. In schizophrenia starting from the first
Çağdaş Eker
doaj +1 more source
Large‐Scale Plasma Proteomics to Profile Pathways and Prognosis of Chronic Pain
Advanced Science, EarlyView.This study delineates both common and site‐specific proteins linked to various chronic pain conditions, elucidating their implications across molecular pathways and health status. These findings, particularly those proteins with genetic causal links to pain or predictive capabilities, have the potential to significantly benefit both research and ...
Ze‐Yu Li +17 more
wiley +1 more source
Clinical overview on RASopathies
American Journal of Medical Genetics Part C: Seminars in Medical Genetics, Volume 190, Issue 4, Page 414-424, December 2022., 2022 Abstract RASopathies comprise a group of clinically overlapping developmental disorders caused by genetic variations affecting components or modulators of the RAS‐MAPK signaling cascade, which lead to dysregulation of signal flow through this pathway.
Martin Zenker
wiley +1 more source
Research progress of neuron-specific enolase in cognitive disorder: a mini review
Frontiers in Human NeuroscienceNumerous studies have demonstrated that neuron-specific enolase (NSE) serves as a distinctive indicator of neuronal injury, with its concentration in blood reflecting the extent and magnitude of nervous system damage, and the expression of serum NSE is ...
Fang Liu +4 more
doaj +1 more source
MultiConAD: A Unified Multilingual Conversational Dataset for Early Alzheimer's Detection [PDF]
arXivDementia is a progressive cognitive syndrome with Alzheimer's disease (AD) as the leading cause. Conversation-based AD detection offers a cost-effective alternative to clinical methods, as language dysfunction is an early biomarker of AD. However, most prior research has framed AD detection as a binary classification problem, limiting the ability to ...
arxiv
Management of Cognitive Dysfunction [PDF]
The Journal of nutrition, health and aging, 2021 openaire +2 more sources
Room B, 10/17/2000 9: 00 AM - 11: 00 AM (PS) Postoperative Cognitive Dysfunction Is Associated with Cerebral Oxygen Desaturations [PDF]
, 2000 Terri G. Monk +3 more
openalex +1 more source
Advanced Science, EarlyView.By investigating auditory hyperexcitability in a mouse model for hereditary deafness, this study identified a subpopulation of afferent neurons of the auditory nerve marked by Otogl expression. Despite their apparently normal hearing, Otogl+/− mice display poor activation of afferent neurons processing loud sounds and an elevation of the middle the ear
Mathilde Gagliardini +24 more
wiley +1 more source
All opinions are not equal: Toward a consensual approach to the development of drug policy
Australian Journal of Social Issues, Volume 57, Issue 4, Page 812-828, December 2022., 2022 Abstract Drug policy has been subjected to much scrutiny from different stakeholder groups who present sometimes very different opinions on solutions to address a problem. Reconciling such differences, that are underpinned by both anecdotal and empirical evidence, is a priority yet to be fully achieved.
Gabriel T. W. Wong, Matthew Manning
wiley +1 more source
Advanced Science, EarlyView.As a plant‐derived flavonoid, apigenin directly targets PRDX6 to inhibit its PLA2 activity, blocking HSPA8 activation and disturbing its interactions with ATM and p38MAPK in senescent cells. By dampening wide spectrum expression of the SASP, apigenin prevents loss of tissue homeostasis, improves organ function, and alleviates multiple age‐related ...
Hongwei Zhang +10 more
wiley +1 more source