Results 161 to 170 of about 339,240 (318)

MTCH2 Suppresses Thermogenesis by Regulating Autophagy in Adipose Tissue

Advanced Science, EarlyView.
This study demonstrates that MTCH2 acts as an evolutionarily conserved regulator of energy homeostasis across Drosophila, rodents, and humans. Adipose‐specific MTCH2 ablation enhances brown/beige adipose thermogenesis through Bcl‐2‐dependent autophagy, promoting energy expenditure and counteracting obesity‐associated metabolic disorders. These findings
Xin‐Yuan Zhao, Ben‐Chi Zhao, Hui‐Lin Li, Ying Liu, Bei Wang, An‐Qi Li, Tian‐Shu Zeng, Hannah Xiaoyan Hui, Jia Sun, Domagoj Cikes, Nele Gheldof, Jorg Hager, Jian‐Xun Mi, D. Ross Laybutt, Yin‐Yue Deng, Yan‐Chuan Shi, G. Gregory Neely, Qiao‐Ping Wang   +17 more
wiley   +1 more source

The construct validity and clinical utility of the Frank Jones Story: a brief screening of cognitive dysfunction

, 2000
K. Bechtold, M. Horner, L Labbate
openalex   +1 more source

Longitudinal, Multimodal Tracking Reveals Lasting Neurovascular Impact of Individual Microinfarcts

Advanced Science, EarlyView.
Jin et al. investigate the neurovascular impact of microinfarcts, revealing transient neural suppression with minimal cell death and recovery linked to vascular remodeling. Fast‐spiking interneurons exhibit reduced excitability, whereas regular‐spiking neurons showed increased bursting activity. Disruptions in low‐gamma phase locking suggest persistent
Yifu Jin, Fei He, Haad Rathore, Yingchu Sun, Jia‐ao Zhang, Xinyu Li, Rongkang Yin, Hanlin Zhu, Chong Xie, Lan Luan   +9 more
wiley   +1 more source

Brain potentials and cognitive dysfunction in schizophrenia. [PDF]

, 1990
Dorothy P. Holinger
openalex  

Abnormal Serum Sodium and Chloride Concentrations May Contribute to Cognitive Dysfunction during Severe Isovolemic Anemia [PDF]

, 2001
E. Lynne Williams
openalex   +1 more source

Regulation of PVT‐CeA Circuit in Deoxynivalenol‐Induced Anorexia and Aversive‐Like Emotions

Advanced Science, EarlyView.
The study investigates Deoxynivalenol (DON) effects on feeding and emotions, focusing on the central amygdala (CeA). Acute DON exposure reduces food intake and alters behavior, linked to CeAGABA neuron activity and PVT‐CeA connectivity. Manipulating CeAGABA neurons and using SCN10A antagonist A‐803467 alleviate DON's effects, offering potential ...
Liu‐Nan Yang, Mingmeng Tang, Andreas K. Nüssler, Liegang Liu, Wei Yang   +4 more
wiley   +1 more source

Gut microbiota‐derived metabolite trimethylamine N‐oxide aggravates cognitive dysfunction induced by femoral fracture operation in mice

Kaohsiung Journal of Medical Sciences
An increasing number of elderly individuals are experiencing postoperative cognitive dysfunction (POCD) problems after undergoing hip replacement surgery, with gut microbiota metabolites playing a role in its pathogenesis.
Ying Xiong, Ya‐Nan Pu, Li‐Ya Li, Yang Su, Jia‐Yuan Niu, Zhao‐Yang Xiao   +5 more
doaj   +1 more source

Cognitive Dysfunction among the Elderly Evaluated by the Cognitive Abilities Screening Instrument (CASI).

, 2000
Michiko Yamada, Yasuyo Mimori, Hideo Sasaki, Junko Ikeda, Shigenobu Nakamura, Kazunori Kodama   +5 more
openalex   +2 more sources

Photo‐Biomodulation of the Hippocampus Using Near‐Infrared Laser to Enhance Cognitive Function in Mice

Advanced Science, EarlyView.
Here a transcranial photo‐biomodulation approach is developed using near‐infrared (NIR) laser on hippocampus of mice, revealing significant improvements in learning and memory ability of mice under normal and disease conditions. The improvement results from the high‐density cell‐induced NIR local energy deposition, neuronal activation, and axonogenesis
Wei‐Tong Pan, Han‐Wen Gu, Yan‐Bo Zhou, Sophie Ma, Daqing Ma, Pan‐Miao Liu, Jian‐Jun Yang   +6 more
wiley   +1 more source

Heart Rate and its Variability from Short-term ECG Recordings as Biomarkers for Detecting Mild Cognitive Impairment in Indian Population [PDF]

arXiv
Alterations in Heart Rate (HR) and Heart Rate Variability (HRV) can reflect autonomic dysfunction associated with neurodegeneration. We investigate the influence of Mild Cognitive Impairment (MCI) on HR and its variability measures in the Indian population by designing a complete signal processing pipeline to detect the R-wave peaks and compute HR and ...
arxiv