Results 171 to 180 of about 554,242 (284)

Inhibition of SLC11A1‐Mediated Lysosomal Iron Accumulation in Microglia Promotes Repair Following White Matter Stroke

Advanced Science, EarlyView.
Genetic and pharmacological inhibition of SLC11A1 functioning as an H+/Fe2+ antiporter–mediated lysosomal iron accumulation in microglia promotes lysosomal lumen acidification, increases CTSD expression, enhances lysosomal myelin debris uptake and degradation, and promotes repair following white matter stroke. ABSTRACT White matter stroke (WMS) results
Lingling Qiu, Yajie Zhang, Yushi Tang, Hongli Hu, Ying Zhang, Junwen Xue, Hao Wang, Yecheng Wang, Chunfeng Liu, Jia Jia, Jian Cheng, Yongjun Cao   +11 more
wiley   +1 more source

A review of brain research on T2DM-related cognitive dysfunction. [PDF]

Open Med (Wars)
Liu Q, Dai S, Li X, Chen Y, Wang N, Wu J, Zhou Y, Yan B, Guo Y, Liu Y.   +9 more
europepmc   +1 more source

RELATIONSHIP OF ASYMMETRY OF COGNITIVE EVOKED POTENTIALS P300 LATENCIES AND EFFECT OF COMBINED THERAPY IN THE ELDERLY WITH HYPERTENSION AND COGNITIVE DYSFUNCTION

, 2019
Dmitry Kovalev, Anatoly Kurzanov, Vitaly Skibitsky, А. И. Пономарева   +3 more
openalex   +1 more source

Activity of Choline Alphoscerate on Adult-Onset Cognitive Dysfunctions: A Systematic Review and Meta-Analysis

, 2023
Getu Gamo Sagaro, Enea Traini, Francesco Amenta   +2 more
openalex   +2 more sources

Adenylyl Cyclase 8 in Dorsal CA1 Neurons Prevents Depressive‐Like Behaviors by Maintaining Neuronal Excitability and Glutamatergic Neurotransmission Through TIP39‐PTH2R Signaling

Advanced Science, EarlyView.
Depression, a prevalent neuropsychiatric disorder with unclear pathogenesis, involves dysfunctional adenylyl cyclase 8 (Adcy8) as a key risk factor. Chronic stress selectively reduces Adcy8 expression in the dorsal CA1 (dCA1) neurons. Depletion of Adcy8 in dCA1 excitatory neurons induces depressive‐like behaviors by impairing neuronal excitability and ...
Zi‐Jie Liu, Jia‐Rui Bi, Zong‐Yan Yu, Meng Tian, Zhi‐Yue Chen, Ran Wei, Miao‐Miao Wang, Hai‐Wei Zha, Yu‐Qing Zhang, Hong‐Jing Wang, Bang‐You Qiang, Shuang‐Shuang Sun, Xiao‐Juan Zhu, Wen‐Bing Chen, Dong Sun   +14 more
wiley   +1 more source

Evaluation of the safety and efficacy of a donepezil depot injection in dogs with canine cognitive dysfunction. [PDF]

Front Vet Sci
Kang MH, Kang MA, Jeon HJ, Shin HC, Moon H, Lee DG, Park HM.   +6 more
europepmc   +1 more source

Olfactory‐to‐Entorhinal Network Dysrhythmias Drive Parkinson's Cognitive Impairment Through Frequency‐Specific Oscillatory Decoupling

Advanced Science, EarlyView.
Wang et al reveal that in the olfactory system, the selective impairment of gamma‐driven Barcode features underlying early olfactory deficits, while the selective impairment of theta‐driven Barcode features underlying later cognitive deficits, further establishing cross‐network gamma oscillations in the early stage as a biomarker of later cognitive ...
Shuaishuai Wang, Zhishen Cai, Xingfeng Mao, Yixuan Zhang, Yunlong Pan, Jiawen Cheng, Xuechun Wang, Hengyi Song, Sasaki Takuya, Ming Lu, Gang Hu, Xiuxiu Liu, Yingmei Lu, Feng Han   +13 more
wiley   +1 more source

Mechanism of Tiaogeng decoction in a cognitive dysfunction mouse model. [PDF]

J Tradit Chin Med
Shuang NI, Xiaofei L, Xiaoyan G, Zuxi GU, Panqing WU, Chao C, Shengnan LI, Xianwei G, Lianwei XU.   +8 more
europepmc   +1 more source

Ferroptosis‐Mediated Hippocampal Neuronal Loss Post‐mTBI: Chromatin Accessibility Profiling and Single‐Nucleus Transcriptomics

Advanced Science, EarlyView.
Hippocampal single ‐nucleus transcriptomes and chromatin accessibility after mild traumatic brain injury reveal dentate granule neuron vulnerability driven by ferroptosis. The c‐Jun–Tmsb4x–Slc2a2 axis modulates lipid peroxidation and iron dysregulation.
Manrui Li, Qiuyun Yang, Shengqiu Qu, Yang Chen, Yang Shen, Yang Xu, Xilong Lin, Yihan Sun, Ying Chen, Meili Lv, Lin Zhang, Zengqiang Yuan, Weibo Liang, Xiameng Chen   +13 more
wiley   +1 more source

Anaemia as a Determinant of Cognitive Dysfunction in Peritoneal Dialysis Patients: Evidence from a Single-Centre Study. [PDF]

Medicina (Kaunas)
Joldić MN, Aranđelović B, Vojnović J, Novaković D, Slavik B, Knežević M, Milutinović D.   +6 more
europepmc   +1 more source