Results 271 to 280 of about 339,240 (318)

Cholinergic Degeneration and Cognitive Function in Early GBA1‐Related Parkinson's Disease

open access: yesAnnals of Neurology, EarlyView.
Objective The phenotype of patients with Parkinson's disease carrying GBA1 variants (GBA‐PD) suggest similarities to symptomatology associated with early cholinergic system degeneration. Therefore, this study aims to investigate the clinical features and the cholinergic innervation pattern in patients with early GBA‐PD versus those without the GBA1 ...
Sofie Slingerland   +6 more
wiley   +1 more source

Clinical factors associated with pneumocystis pneumonia despite its primary prophylaxis: When to stop prophylaxis?

open access: yesArthritis &Rheumatology, Accepted Article.
Objective Although previous studies show that primary prophylaxis against Pneumocystis jirovecii pneumonia (PJP) is effective in patients with rheumatic diseases receiving immunosuppressive treatment, there is limited evidence regarding the optimal timing for prophylaxis withdrawal.
Ju Yeon Kim   +5 more
wiley   +1 more source

Optimized 5-HT<sub>2b</sub> inhibitors for neuropsychiatric syndromes with cognitive dysfunction. [PDF]

open access: yesAlzheimers Dement (N Y)
Roy SM   +8 more
europepmc   +1 more source

Age‐Dependent Effects of Loss of Contactin‐Associated Protein‐Like 2, an Autism‐Associated Gene, on the Acquisition and Recall of Fear Memory

open access: yesAutism Research, EarlyView.
ABSTRACT The contactin‐associated protein‐like 2 (Cntnap2) gene is relevant to autism spectrum disorder (ASD), which is associated with age‐specific structural alterations in limbic brain regions. The Cntnap2 gene encodes for the contactin‐associated protein‐like 2 (CASPR2) protein, and CASPR2 protein levels are high in the amygdala, a limbic region ...
R. J. Taugher‐Hebl   +7 more
wiley   +1 more source

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