Results 111 to 120 of about 211,599 (291)

Brain and Liver Dual‐Targeting Oridonin Nanoparticles to Enhance Aβ Clearance for Alzheimer's Disease Therapy

open access: yesAdvanced Science, EarlyView.
We developed a nanoparticle named OAF, which simultaneously targeted to both the brain and liver via the transferrin receptor 1 (TfR1) receptor, promoting lipoprotein receptor‐related protein 1 (LRP1) expression to enhance amyloid‐beta (Aβ) clearance. In AD mice model, OAF significantly reduced Aβ deposition and cognitive impairment, while a mitigating
Wenshuai Gong   +8 more
wiley   +1 more source

Cognitive Fatigue Influences Time-On-Task During Bodyweight Resistance Training Exercise

open access: yesFrontiers in Physiology, 2016
Prior investigations have shown measurable performance impairments on continuous physical performance tasks when preceded by a cognitively fatiguing task.
James Head   +5 more
doaj   +1 more source

Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing

open access: yesAdvanced Science, EarlyView.
Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale   +6 more
wiley   +1 more source

Sleep Deprivation Effects on Cognitive Performance

open access: yes, 2011
An experimental sleep deprivation study has been launched at the German Aerospace Center (DLR) in order to determine effects of varying degrees of sleepiness and alcohol on cognitive performance.
Elemenhorst, Eva-Maria   +7 more
core  

Schooling Trajectories and the Development of Brain Dynamics: A Comparative Study of Montessori and Traditional Education

open access: yesAdvanced Science, EarlyView.
We investigate whether Montessori and traditional schooling systems shape the developmental trajectory of large‐scale brain dynamics in different ways. We quantify the arrow of time (“non‐reversibility”) in neural activity during resting state and movie‐watching, revealing distinct maturational patterns.
Elvira del Agua   +6 more
wiley   +1 more source

Study on exhaled volatile organic compounds identifying cognitive fatigue induced by N-back task in healthy young adults

open access: yesEcotoxicology and Environmental Safety
Cognitive fatigue in specific occupations may present a risk to personal safety. The study aimed to explore the characteristic volatile organic compounds (VOCs) in exhaled breath in response to cognitive fatigue, to provide a scientific basis for the non-
Xiaoyu Zhang   +4 more
doaj   +1 more source

Ferroelectric Devices for In‐Memory and In‐Sensor Computing

open access: yesAdvanced Science, EarlyView.
Inspired by biological systems, in‐memory and in‐sensor computing overcome von Neumann bottlenecks. Ferroelectric devices can mimic synaptic functions and sense stimuli like light or force, therefore are ideal for these paradigms. This review introduces the ferroelectric devices applied for in‐memory and in‐sensor computing, covering their structures ...
Hong Fang   +5 more
wiley   +1 more source

Central and peripheral manipulations of perceived exertion and endurance performance [PDF]

open access: yes, 2014
Perception of effort, defined as “the conscious sensation of hard, heavy and strenuous exercise”, is known to regulate endurance performance and human behaviour.
Pageaux, Benjamin
core  

The Flush Model: A Novel Framework to Manage Surgeons’ Mental Fatigue and Cognitive Load

open access: yesAnnals of Surgery Open
Background:. Mental fatigue significantly impairs surgeons’ cognitive performance, compromising patient safety. However, surgical practice lacks an integrated framework to understand and mitigate this cognitive strain effectively. Conceptual Model:.
Pierrick Laulan, PhD   +4 more
doaj   +1 more source

Advances and Perspectives in Graphene‐Based Quantum Dots Enabled Neuromorphic Devices

open access: yesAdvanced Science, EarlyView.
Graphene‐based QDs are zero‐dimensional carbon nanomaterials with pronounced quantum confinement and tunable electronic structures. Herein, we summarize their synthesis strategies and functionalization methods, and highlight their functional roles and operating mechanisms in devices, as well as recent advances in neuromorphic electronics. We anticipate
Yulin Zhen   +9 more
wiley   +1 more source

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