Results 171 to 180 of about 2,616,197 (253)

Molecular Glue Degraders Enhance CAPRIN1‐Dependent Lysosomal Degradation of APP and Reduce Amyloid β in Alzheimer's Disease

open access: yesAdvanced Science, EarlyView.
A new class of lysosome‐directed molecular glue degraders selectively enhance CAPRIN1–APP interactions, driving APP degradation and reducing amyloid‐β production in human neurons and Alzheimer's disease mouse models. This CAPRIN1‐dependent targeted protein degradation strategy reveals a previously unrecognized therapeutic approach for disrupting the ...
Sunghan Jung   +15 more
wiley   +1 more source

Tri‐Functional Electrocatalysis for Zinc–Air Battery Coupled Water Splitting: A Catalyst‐Electrode‐Device‐System Perspective

open access: yesAdvanced Science, EarlyView.
This review establishes a catalyst–electrode–device–system framework for tri‐functional HER/OER/ORR electrocatalysis that couples water splitting with Zn–air batteries. Five catalyst families are covered: noble‐metal, metal‐based, single‐atom, heterostructure, and metal‐free systems.
Xixi Di   +9 more
wiley   +1 more source

Strategies and Challenges in Memristor‐Selector Integration for High‐Density Memory and Compute‐in‐Memory Systems

open access: yesAdvanced Electronic Materials, EarlyView.
Selector integration enables scalable memristor crossbar arrays by suppressing sneak‐path currents and improving array selectivity. This review summarizes integration strategies, device requirements, challenges, and opportunities for high‐density memory, compute‐in‐memory, and neuromorphic computing systems.
Zohreh Hajiabadi   +3 more
wiley   +1 more source

Cost‐Effective Ti/Al/Ni Multilayer Neural Probes With In Vivo Recording Performance Comparable to Ti/Au Neural Probes

open access: yesAdvanced Electronic Materials, EarlyView.
In this study, we developed a cost‐efficient neural probe by replacing traditional gold with an aluminum‐based Ti/Al/Ni multilayer stack. Optimizing this metal architecture suppressed oxidation and ensured robust electrical stability, achieving signal quality comparable to standard gold probes. It enables a highly accessible and economical solution for
Sehwan Park   +6 more
wiley   +1 more source

How Video‐Based Information Affects Farmers' Willingness to Pay for Drone Services

open access: yesApplied Economic Perspectives and Policy, EarlyView.
ABSTRACT Professional service for digital technology like agricultural drones lowers transaction costs and scope thresholds for smallholders. Meanwhile, perceptual adoption barriers remain underexplored. We conduct a two‐stage choice experiment with a randomized video‐based information treatment among 384 Chinese crop farmers to measure its effect on ...
Hua Zhang   +4 more
wiley   +1 more source

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