Results 181 to 190 of about 764,861 (288)

Human subjects exploit a cognitive map for credit assignment. [PDF]

Proc Natl Acad Sci U S A, 2021
Moran R, Dayan P, Dolan RJ.
europepmc   +1 more source

CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao, Rong Li, Yu‐Xiang Jiao, Kai Ma, Hong‐Qi Yang, Zheng‐Yu Sun, Jie‐Wen Zhang, Shuai Chen   +7 more
wiley   +1 more source

Curiosity shapes spatial exploration and cognitive map formation in humans. [PDF]

Commun Psychol
Cen D, Teichert E, Hodgetts CJ, Gruber MJ.   +3 more
europepmc   +1 more source

Cognitive map formation through haptic and visual exploration of tactile city-like maps. [PDF]

Sci Rep, 2021
Ottink L, Hoogendonk M, Doeller CF, Van der Geest TM, Van Wezel RJA.   +4 more
europepmc   +1 more source

SPG4 and Dementia: Expanding the Clinical Spectrum

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza, Arun Meyyazhagan, Eliseo Picchi, Gustavo Ribas, Ingrid Faber, Ryosuke Miyamoto, Preethi Basavaraju, Paolo Eusebi, Haripriya Kuchi Bhotla, Mario Stasi, Fabrizio Gaudiello, Francesco Patti, Filippo Maria Santorelli, Marcondes Cavalcante França Jr, José Luiz Pedroso, Orlando Graziani Povoas Barsottini, Hélio Afonso Ghizoni Teive, Peter Henry St George‐Hyslop, Toshitaka Kawarai, Antonio Orlacchio   +19 more
wiley   +1 more source

Pre-protocol of the Virtual Spatial Configuration Task (VSCT): A Novel Virtual Reality-Based Tool for Assessing Cognitive Map Formation Abilities. [PDF]

Open Res Eur
Umiltà AM, Li Pira G, Burles F, Ottoboni G, Tessari A.   +4 more
europepmc   +1 more source

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

The medial and lateral orbitofrontal cortex jointly represent the cognitive map of task space. [PDF]

Commun Biol
Tan L, Qiu Y, Qiu L, Lin S, Li J, Liao J, Zhang Y, Zou W, Huang R.   +8 more
europepmc   +1 more source

COVID-19 and Sustainable Development Goals (SDGs): Scenario analysis through fuzzy cognitive map modeling. [PDF]

Gondwana Res, 2023
Ameli M, Shams Esfandabadi Z, Sadeghi S, Ranjbari M, Zanetti MC.   +4 more
europepmc   +1 more source

Effectiveness of rTMS on Working Memory and Inhibitory Impairments in Patients With Post‐Stroke Executive Deficits

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Considerable efforts have been dedicated to developing effective treatments for post‐stroke executive impairment (PSEI), among which repetitive transcranial magnetic stimulation (rTMS) has shown great potential. This study aimed to investigate the therapeutic effects of high‐frequency rTMS on working memory (WM) and response ...
Mengting Lao, Rongwei Du, Zhujun Wang, Yang Gao, Meiling Cheng, Xianglong Wang, Wen Wu   +6 more
wiley   +1 more source