Results 111 to 120 of about 2,391,721 (300)

White Matter Microstructural Abnormalities in Neonatal Onset Genetic Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Recent evidence indicates that epilepsy is associated with abnormal white matter. If seizures alter white matter, then the impact upon network function, epileptogenesis, and cognition could be pronounced in neonates undergoing rapid developmental myelination. Neonates with epilepsy due to nonstructural genetic causes provide a unique
Amanda G. Sandoval Karamian, Tianjia Zhu, Hao Huang, Shavonne L. Massey, Mark P. Fitzgerald, Darshana Parikh, Arastoo Vossough, Ingo Helbig, Nicholas S. Abend   +8 more
wiley   +1 more source

Oscillatory dynamics of active learning in the human brain

Comunicació presentada al 2019 Conference on Cognitive Computational Neuroscience, celebrada a Berlin (Alemanya) del 13 al 16 de setembre de 2019.While the benefits of self-directed learning on human memory are well-acknowledged, little is known on its ...
Axmacher, Nikolai, Principe, Alessandro, Rocamora Zúñiga, Rodrigo Alberto, Pacheco Estefan, Daniel, Verschure, Paul F. M. J., Arsiwalla, Xerxes D., Zucca, Riccardo   +6 more
core   +1 more source

Unravelling the “equivalence paradox”: An exploration of possible mechanistic explanations for the equivalence of the person-centred approach and cognitive behavioural therapy [PDF]

, 2011
This project adopted a neuroscience perspective to explore the reason for the Equivalence Paradox, that is the finding that quite different therapeutic modalities are, as an approximation, equally effective.
Garman, Andrew J.
core   +2 more sources

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers, Yaqiao Wei, Dinesh K. Deelchand, Adam Berrington, Young Woo Park, Guita Banan, Michal Povazan, Jens T. Rosenberg, André J. W. van der Kouwe, Tetsuo Ashizawa, Khalaf O. Bushara, Chiadi U. Onyike, Sub H. Subramony, Jeremy D. Schmahmann, Brian J. Soher, Peter B. Barker, Thomas H. Mareci, Eva‐Maria Ratai, Lynn E. Eberly, Gülin Öz   +19 more
wiley   +1 more source

Scaling up the Evaluation of Recurrent Neural Network Models for Cognitive Neuroscience

, 2022
Li, Moufan, Moufan Li, Guangyu Robert Yang, Nathan Cloos, Cueva, Christopher J, Cloos, Nathan, Christopher J. Cueva, Yang, Guangyu Robert   +7 more
core   +1 more source

Electroencephalographic Normalization as a Biomarker of Clinical Recovery in Down Syndrome Regression Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Down syndrome regression disorder is a syndrome characterized by subacute loss of cognitive, behavioral, and functional abilities in individuals with Down syndrome. Electroencephalography abnormalities are frequently observed during evaluation, but it remains unclear whether these findings represent a dynamic marker of disease ...
Jonathan D. Santoro, Mackenzie Silverman, Maeve C. Lucas, Mariam M. Yousuf, Samuel T. Otey, Stella V. Gray, Brittany Jordan, Madeline D. Kahan, Latanya D. Agurs, Michelle Van Hirtum Das, Deborah Holder, Devin King, Eileen A. Quinn, Ryan Kammeyer, Michael S. Rafii   +14 more
wiley   +1 more source

Behavioral observation of xenopus tadpole swimming for neuroscience labs [PDF]

, 2014
Neuroscience labs benefit from reliable, easily - monitored neural responses mediated by well - studied neural pathways . Xenopus laevis tadpoles have been used as a simple vertebrate model preparation in motor control studies.
Porter, Nicola Jean, Li, Wenchang, Wagner, Monica Anne   +2 more
core   +1 more source

Convolutional neural networks develop major organizational principles of early visual cortex when enhanced with retinal sampling

Scientific Reports
Primate visual cortex exhibits key organizational principles: cortical magnification, eccentricity-dependent receptive field size and spatial frequency tuning as well as radial bias.
Danny da Costa, Lukas Kornemann, Rainer Goebel, Mario Senden   +3 more
doaj   +1 more source

Cognitive and Neuroimaging Divergence Between Juvenile and Adult FUS Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by progressive motor neuron degeneration. Fused in sarcoma (FUS)‐associated juvenile ALS (jALS) represents a distinct and aggressive subgroup with rapid deterioration and poor prognosis.
Alexandra V. Jürs, Marcel Naumann, Annaliis Lehto, Hanna Schön, Jens Kurth, Johannes Prudlo, Andreas Hermann, Elisabeth Kasper   +7 more
wiley   +1 more source

Distinct information flows for different whole-body actions across LOTC subdivisions

Communications Biology
The lateral occipitotemporal cortex (LOTC) is crucial for object, body, and expression perception, but its functions in computing body representation and action information remain poorly understood. Using ultrahigh-field 7 T fMRI and data-driven methods,
Baichen Li, Giuseppe Marrazzo, Marta Poyo Solanas, Beatrice de Gelder   +3 more
doaj   +1 more source