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Influence of cognitive neuroscience on contemporary philosophy of science

Translational Neuroscience, 2019
The study of contemporary philosophy of science based on cognitive neuroscience has strongly promoted the philosophy study of brain cognitive problems.
Ren Fang
doaj   +1 more source

Assessment of cortical inhibition depends on inter individual differences in the excitatory neural populations activated by transcranial magnetic stimulation

Scientific Reports, 2022
Transcranial magnetic stimulation (TMS) is used to probe inhibitory intracortical neurotransmission and has been used to infer the neurobiological dysfunction that may underly several neurological disorders.
Andris Cerins, Daniel Corp, George Opie, Michael Do, Bridgette Speranza, Jason He, Pamela Barhoun, Ian Fuelscher, Peter Enticott, Christian Hyde   +9 more
doaj   +1 more source

Connecting Levels of Analysis in Educational Neuroscience: A Review of Multi-level Structure of Educational Neuroscience with Concrete Examples [PDF]

, 2019
In its origins educational neuroscience has started as an endeavor to discuss implications of neuroscience studies for education. However, it is now on its way to become a transdisciplinary field, incorporating findings, theoretical frameworks and ...
Han, Hyemin
core  

The Neuroscience of Mathematical Cognition and Learning [PDF]

, 2016
The synergistic potential of cognitive neuroscience and education for efficient learning has attracted considerable interest from the general public, teachers, parents, academics and policymakers alike.
Cohen Kadosh, Roi, Krause, Beatrix, Looi, Chung Yen, OECD. Organisation for Economic Cooperation and Development, Thompson, Jacqueline   +4 more
core   +2 more sources

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham, Sahana Sathyanarayana, Charlotte B. Stewart, Robyn Iredale, Victoria Foster, Debra Galley, Mark Baker, Nicola Pavese   +7 more
wiley   +1 more source

Hand preference for the visual and auditory modalities in humans

Scientific Reports, 2021
The sensory dominance effect refers to the phenomenon that one sensory modality more frequently receives preferential processing (and eventually dominates consciousness and behavior) over and above other modalities.
Yuqian Yang, Peter H. Weiss, Gereon R. Fink, Qi Chen   +3 more
doaj   +1 more source

Inconsistencies in atlas-based volumetric measures of the human nucleus basalis of Meynert: A need for high-resolution alternatives

NeuroImage, 2022
The nucleus basalis of Meynert (nbM) is the major source of cortical acetylcholine (ACh) and has been related to cognitive processes and to neurological disorders. However, spatially delineating the human nbM in MRI studies remains challenging.
Yawen Wang, Minye Zhan, Alard Roebroeck, Peter De Weerd, Sriranga Kashyap, Mark J. Roberts   +5 more
doaj   +1 more source

The effect of alpha-2 adrenergic receptors on memory retention deficit induced by rapid eye movement sleep deprivation [PDF]

Iranian Journal of Basic Medical Sciences, 2020
Objective(s): Evidence shows that sleep deprivation (SD) disrupts the formation of hippocampus-related memories. Moreover, α2 adrenergic receptors that are wildly expressed in the CA1 hippocampal region have a significant role in modulating both sleep ...
Yaser Norozpour, Mohammad Nasehi, Vahid Sabouri-Khanghah, Mohammad Nami, Salar Vaseghi, Mohammad-Reza Zarrindast   +5 more
doaj   +1 more source