Results 131 to 140 of about 308,966 (305)
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To characterize the demographic, clinical, and laboratory features of the Chinese patients of genetic Creutzfeldt‐Jakob disease with T188K variant (T188K‐gCJD), the most common subtype of genetic prion diseases (gPrDs) in China. Methods In this nationwide retrospective study, data from 98 genetically confirmed T188K‐gCJD patients ...
Chun‐Jie Li +11 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Digital technologies hold promise for transforming healthcare by enhancing personalized treatments and offer valuable opportunities to improve patient care. Here, we evaluated several novel, self‐administered, home‐based, digital endpoints for their association with corresponding conventional standard clinical measures (primary) in ...
Arne Mueller +14 more
wiley +1 more source
Cognitive profiles across the psychosis continuum
Psychiatry ResearchCognitive impairments are core features in individuals across the psychosis continuum and predict functional outcomes. Nevertheless, substantial variability in cognitive functioning within diagnostic groups, along with considerable overlap with healthy controls, hampers the translation of research findings into personalized treatment planning.
Tina D. Kristensen +11 more
openaire +5 more sources
Cognitive profile of individuals with borderline intellectual functioning: a systematic review
This research was funded by the Ministry of Science, Innovation and Universities through the University Teacher Training Program (reference FPU2022-02193) and by the Department of Research and Psychology in Education of the Faculty of Education - Teacher
López Escribano, María Del Carmen +2 more
core +1 more source
, 2013 Background/Aims: To identify prodromal Alzheimer's disease (AD) subjects using a data-driven approach to determine cognitive profiles in mild cognitive impairment (MCI).Methods: A total of 881 MCI subjects were recruited from 20 memory clinics and ...
Almkvist, Ove,, Damian, M.
core +1 more source
Keep Calm and Learn the Language: Do Multilinguals Have Lower Intolerance of Uncertainty than Monolinguals? [PDF]
, 2020 This paper presents the results of an observational study on therelationship between multilingualism and lower Intolerance ofUncertainty (IoU). A group of over two hundred multilingualand monolingual individuals filled in an online survey that con-tained
M ̈uller, Lisa-Maria +5 more
core
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw +5 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Down syndrome regression disorder is a syndrome characterized by subacute loss of cognitive, behavioral, and functional abilities in individuals with Down syndrome. Electroencephalography abnormalities are frequently observed during evaluation, but it remains unclear whether these findings represent a dynamic marker of disease ...
Jonathan D. Santoro +14 more
wiley +1 more source
Risk and resilience in cognitive ageing
, 2019 Whilst advancing age is, on average, associated with declining cognitive abilities, the course of cognitive ageing is highly variable at the individual level.
O'Donoghue, Melissa Clare
core +1 more source
Inflammatory biomarkers profiles and cognition among older adults
Scientific ReportsInflammation plays a major role in cognitive aging. Most studies on peripheral inflammation and cognitive aging focused on selected major inflammatory biomarkers.
Aline Thomas +9 more
doaj +1 more source