Results 71 to 80 of about 366,624 (300)

Discovery of a Novel and Potent Kir4.1 Inhibitor as a Safe and Rapid‐Onset Antidepressant Agent in Mice

open access: yesAdvanced Science, EarlyView.
The preferred derivative JX3212 demonstrates strong inhibitory activity against Kir4.1 with favorable druggability and shows significant antidepressant efficacy in vivo. Abstract Major depressive disorder is a serious psychiatric disorder for which novel and fast‐acting antidepressants are required.
Sisi Wang   +15 more
wiley   +1 more source

Parabiosis, Assembloids, Organoids (PAO)

open access: yesAdvanced Science, EarlyView.
This review evaluates parabiosis, organoids, and assembloids as complementary disease models spanning systemic, organ, and multi‐organ levels. It highlights their construction strategies, applications, and current limitations, while emphasizing their integration with frontier technologies such as artificial intelligence, organ‐on‐a‐chip, CRISPR, and ...
Yang Hong   +5 more
wiley   +1 more source

A Virtual Clinical Trial of Psychedelics to Treat Patients With Disorders of Consciousness

open access: yesAdvanced Science, EarlyView.
Disorders of consciousness after severe brain injury are marked by reduced complexity of brain activity and limited treatment options. Using personalized whole‐brain models, this study shows that simulated lysergic acid diethylamide (LSD) and psilocybin shift patient brain dynamics closer to criticality.
Naji L.N. Alnagger   +17 more
wiley   +1 more source

Pratiche didattiche dei docenti: risultati di un questionario proposto all’Università di Trento

open access: yesJournal of Educational, Cultural and Psychological Studies
ACADEMICS’ TEACHING PRACTICES: RESULTS FROM A QUESTIONNAIRE AT UNIVERSITY OF TRENTO Abstract The paper presents a survey conducted by the TLC of the University of Trento aimed at identifying the teaching methodologies adopted by professors, detected ...
Sabrina Maniero   +4 more
doaj   +1 more source

Using cognitive psychology to understand GPT-3. [PDF]

open access: yesProc Natl Acad Sci U S A, 2023
Binz M, Schulz E.
europepmc   +1 more source

The Adaptive Physical Activity Study in Stroke (TAPAS): A Feasibility Sequential Multiple Assignment Randomized Trial

open access: yesAdvanced Science, EarlyView.
This study examines the feasibility of a mobile health physical activity intervention for individuals post‐stroke using a sequential multiple assignment randomized trial (SMART) design. High recruitment, retention, and adherence rates are observed, with promising trends in step count, fatigue, and quality of life.
Aoife Whiston   +20 more
wiley   +1 more source

Working towards Usable Forms on the World Wide Web: Optimizing Date Entry Input Fields

open access: yesAdvances in Human-Computer Interaction, 2011
When an interactive form in the world wide web requires users to fill in exact dates, this can be implemented in several ways. This paper discusses an empirical online study with n = 172 participants which compared six different versions to design input ...
Javier A. Bargas-Avila   +4 more
doaj   +1 more source

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