Imipramine plus cognitive behavioural therapy (CBT) was more effective than placebo plus CBT in adolescents with comorbid anxiety and depression who refused to attend school [PDF]
John S. March
openalex +1 more source
Neural Patterns of Social Pain in the Brain‐Wide Representations Across Social Contexts
Empathy arises from both physiological and social pain, yet their shared and context‐specific neural mechanisms remain unclear. Combining fMRI and multivariate pattern analysis, this study decodes overlapping empathy networks and distinct representations for social exclusion versus separation.
Xiaodong Zhang+11 more
wiley +1 more source
Randomised controlled trial of non-directive counselling, cognitive-behaviour therapy, and usual general practitioner care for patients with depression. II: Cost effectiveness [PDF]
Peter Bower+6 more
openalex +1 more source
Dean Schuyler, Jeffrey S. Cluver
openaire +3 more sources
Arf1 defects activate the AKT‐mTORC1‐SREBP1‐FASN pathway to increase lipid synthesis and disrupt ER‐mitochondrial‐lysosomal homeostasis in neurons. Impaired mitochondria secrete damaged mtDNA via mitochondria‐derived extracellular vesicles, which is phagocytosed by the microglia and activated inflammation signaling.
Xu Li+10 more
wiley +1 more source
Postoperative cognitive dysfunction (POCD) remains a challenge with no effective treatments. This study introduces a novel hydrogen‐gene therapy strategy, combining focused ultrasound and siRNA delivery via hydrogen emitters, to repair neuroinflammation in a precise and controlled manner.
Ruonan Zhan+11 more
wiley +1 more source
Cognitive‐behavioral group therapy versus phenelzine in social phobia: Long term outcome
Michael R. Liebowitz+11 more
openalex +1 more source
This study presents the NEV β‐secretase activity assay, a groundbreaking method for noninvasive evaluation of β‐secretase activity in Alzheimer's disease (AD) patients, enabling the generation of individualized β‐secretase activity profiles.
Hyoyong Kim+19 more
wiley +1 more source
A Multicenter, Randomized Clinical Study to Evaluate the Effect on Cognitive Function of Topiramate Compared with Valproate as Add‐On Therapy to Carbamazepine in Patients with Partial‐Onset Seizures [PDF]
Albert P. Aldenkamp+15 more
openalex +1 more source
Improving Adult Vision Through Pathway‐Specific Training in Augmented Reality
Traditional perceptual training approaches are limited by stimulus specificity, treatment efficacy, and patient compliance. A novel altered reality (AR) method is developed to enhance pathway‐specific functions in human adults while performing everyday activities.
Yige Gao+4 more
wiley +1 more source