Endothelial PD‐1 Regulates Vascular Homeostasis and Oligodendrogenesis during Brain Development
Vascular endothelial cells are fundamental for angiogenesis and brain development. This study reveals that endothelial programmed cell death 1 (PD‐1) is critical for cerebral angiogenesis and blood brain barrier (BBB) maturation. It also mediates interaction with oligodendrocyte precursor cells (OPCs), modulating OPCs differentiation and myelination ...
Tingting He+7 more
wiley +1 more source
Abstract Children and other vulnerable parties such as those with a cognitive, social or communication impairment frequently struggle to understand, and be understood in, the criminal justice environment. One way this has been addressed in jurisdictions around Australia and overseas is through the introduction of intermediary (or communication partner)
Sarah Hoff, Martine Powell, David Plater
wiley +1 more source
Cognitive behaviour therapy was more effective than interpersonal psychotherapy for bulimia nervosa [PDF]
Cynthia M. Bulik
openalex +1 more source
IFITM2 Modulates Endocytosis Maintaining Neural Stem Cells in Developing Neocortex
This study reveals IFITM2 as a key regulator of endocytosis in radial glial cells (RGCs) during brain development. IFITM2's YXXø motif and phosphoinositide‐binding residues (K82/K87) are essential for endosome formation. IFITM2 deficiency disrupts the embryonic cortical neurogenesis, revealing a conserved mechanism linking endocytic dynamics to neural ...
Yuqing Lv+6 more
wiley +1 more source
All opinions are not equal: Toward a consensual approach to the development of drug policy
Abstract Drug policy has been subjected to much scrutiny from different stakeholder groups who present sometimes very different opinions on solutions to address a problem. Reconciling such differences, that are underpinned by both anecdotal and empirical evidence, is a priority yet to be fully achieved.
Gabriel T. W. Wong, Matthew Manning
wiley +1 more source
Correction: Mindfulness-Based Cognitive Therapy for Treatment-Resistant Depression: A protocol for systematic review and meta-analysis. [PDF]
Rodrigues MF+3 more
europepmc +1 more source
Cognitive Therapy-as-Usual versus Cognitive Therapy plus the Memory Support Intervention for adults with depression: 12-month outcomes and opportunities for improved efficacy in a secondary analysis of a randomized controlled trial. [PDF]
Zieve GG+5 more
europepmc +1 more source
Review: cognitive and behaviour therapies are effective for chronic pain [PDF]
P. Richardson
openalex +1 more source
A novel “prof” cocktail therapy is designed. It screens antigens, selects personalized antigen panels, engineers optimized CAR‐Vδ1 T cells, and tests in patient‐derived GBM organoids, offering hope for effective CAR‐T drugs against heterogeneous solid tumors. Abstract Various challenges, including tumor heterogeneity and inadequate T cell infiltration,
Guidong Zhu+12 more
wiley +1 more source
Comparing the effectiveness of occupational stress training package with mindfulness-based cognitive therapy on job burnout of Tam Kar's employees in order to health promotion. [PDF]
Gorji S.
europepmc +1 more source