Results 211 to 220 of about 6,920,351 (382)

Single Administration of AAV‐mAtp6v1b2 Gene Therapy Rescues Hearing and Vestibular Disorders Caused by Atp6v1b2‐Induced Lysosomal Dysfunction in Hair Cells

Advanced Science, EarlyView.
Wei et al. establish a hair cell‐specific conditional knockout mouse model (Atp6v1b2fl/fl;Atoh1Cre/+), and demonstrate the importance of Atp6v1b2 for hair cell through maintaining the survival of lysosomes. A single administration of AAV‐ie‐Eh3‐mAtp6v1b2 through scala media at P0‐P2 realizes function compensation and restores hearing and balance ...
Gege Wei, Shiwei Qiu, Xue Gao, Lu Zheng, Yijin Chen, Ying Ma, Haifeng Feng, Jinyuan Yang, Guojie Dong, Huiyi Nie, Weihao Zhao, Xiaoge Li, Guangqin Wang, Wei Xiong, Pu Dai, Yongyi Yuan   +15 more
wiley   +1 more source

Effects of cognitive therapy on psychological symptoms and social functioning in residual depression [PDF]

, 2000
Jan Scott, John D. Teasdale, Eugene S. Paykel, Anthony L. Johnson, Rosemary Abbott, Hazel Hayhurst, Richard G. Moore, Ann F. Garland   +7 more
openalex   +1 more source

Rational Design of Inner Ear Drug Delivery Systems

Advanced Science, EarlyView.
Hearing loss is a common disease affecting many people, and inner ear lesions are one of the most important causes. This review focuses on the treatment of inner ear hearing loss by drug delivery systems. It includes the current methods and technologies developed, and it predicts possible directions.
Xiayidan Maimaitikelimu, Zhiyan Xuan, Haoyu Ren, Keng Chen, Hui Zhang, Huan Wang   +5 more
wiley   +1 more source

Mindfulness and MBCT-vision (mindfulness-based cognitive therapy modified for visual symptoms) for visual snow syndrome: a therapeutic perspective. [PDF]

Front Neurol
Wong SH, Wingrove J.
europepmc   +1 more source

Cognitive Behavior Therapy in Panic Disorder and Comorbid Major Depression [PDF]

, 2000
Winfried Rief, Susanne Trenkamp, Claudia Auer, Manfred M. Fichter   +3 more
openalex   +1 more source

Cryptic Splicing of GAP43 mRNA is a Novel Hallmark of TDP‐43‐Associated ALS and AD

Advanced Science, EarlyView.
TDP‐43 dysfunction disrupts RNA processing, inducing cryptic exon 4a1 inclusion in GAP43 and reducing its protein levels. This aberrant splicing impairs axonal regeneration and contributes to neurodegeneration in ALS and AD. RNA‐seq of patient brains reveals GAP43 downregulation and 4a1 upregulation, identifying cryptic exon 4a1 as a potential ...
Mingming Yang, Qi Wang, Dongkun Kang, Shijia Wang, Yanli Jiang, Jian‐Zhi Wang, Chen Ming, Rong Liu, Jianlan Gu, Xiaochuan Wang   +9 more
wiley   +1 more source

A guided internet-delivered mindfulness-based cognitive therapy for insomnia: study protocol for a randomized controlled study. [PDF]

Front Psychiatry
Zeng Z, Liu F, Zhu C, Long X, Jiang J, Huang L, Lu Z.   +6 more
europepmc   +1 more source

Minimizing the cognitive effects of lithium therapy and electroconvulsive therapy using thyroid hormone [PDF]

, 2000
Geoffrey Tremont, Robert A. Stern
openalex   +1 more source

The Efficacy of Cognitive Behavioral Therapy: A Review of Meta-analyses

Cognitive Therapy and Research, 2012
S. Hofmann, Anu Asnaani, I. Vonk, Alice T. Sawyer, A. Fang   +4 more
semanticscholar   +1 more source

Genetics‐Based Targeting Strategies for Precise Neuromodulation

Advanced Science, EarlyView.
In this Review, the fundamental principles and implementation protocols of genetics‐based precision neuromodulation are first introduced. Then, wireless and low‐invasive strategies based on nano‐transducing materials are highlighted, along with a dissection and analysis of the strengths and weaknesses of representative studies.
Yuyuan He, Zhidong Wei, Jianda Xu, Fei Jin, Tong Li, Lili Qian, Juan Ma, Weiying Zheng, Negar Javanmardi, Ting Wang, Kangjian Sun, Zhang‐Qi Feng   +11 more
wiley   +1 more source