Results 41 to 50 of about 138,186 (293)

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Mapping spin-correlations with hard X-ray free-electron laser [PDF]

open access: yesEPJ Web of Conferences, 2019
Time-resolved X-ray diffraction from Ga091Mn0 09As was recorded with a hard X-ray free-electron-laser. The influence of spin-orders on phonons was investigated; our result suggests a new method for mapping the spin-correlations in low doped magnetic ...
Zhong Yinpeng   +12 more
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

The Statistical Mechanics of Ideal Magnetohydrodynamic Turbulence and a Solution of the Dynamo Problem

open access: yesFluids
We review and extend the theory of ideal, homogeneous, incompressible, magnetohydrodynamic (MHD) turbulence. The theory contains a solution to the ‘dynamo problem’, i.e., the problem of determining how a planetary or stellar body produces a global dipole
John V. Shebalin
doaj   +1 more source

Emergence of Nonzonal Coherent Structures [PDF]

open access: yes, 2019
17 pages, 14 figures, submitted to "Zonal jets" by Galperin B. and Read, P.L. (eds.).
Bakas, Nikolaos A., Ioannou, Petros J.
openaire   +2 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Coherence, focus and structure [PDF]

open access: yesPragmatics. Quarterly Publication of the International Pragmatics Association (IPrA), 2022
This paper examines the usage of NE in Chinese dialogues and monologues excerpted from a Chinese collection of narratives. The analysis of NE as a constituent in discourse structure shows that linguistically it functions like a grammatical connector. From a cognitive point of view, NE signals topic shift and focuses on new, contrastive information.
openaire   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Home - About - Disclaimer - Privacy