Results 31 to 40 of about 13,311 (261)
Learning processes and economic returns [PDF]
Investigaciones Regionales - Journal of Regional Research, 2013 This paper evaluates whether the learning mechanisms of the European Cohesion policy have contributed to improve the economic impact of Structural Fund expenditure over time. It analyses whether the evolution of the policy in response to greater internal
Andrés Rodríguez-Pose, Katja Novak
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Significance of the EU funds in regional development on the example of NUTS-3 units in Poland
Research Papers in Economics and Finance, 2021 Within the EU cohesion policy, better and worse developed regions are subcategorised, taking account of the GDP value per capita. Based on that, areas qualifying for obtaining support from aid programs from the EU budget are established.
Joanna Spychała, Marcin Spychała
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FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Przedsięwzięcia prośrodowiskowe finansowane ze środków funduszy unijnych
Prawne Problemy Górnictwa i Ochrony Środowiska, 2021 The EU promotes the implementation of pro-ecological solutions in the member states to restore the environment in order to improve the living conditions of the citizens. Co-financing for the implementation of projects supporting the protection of climate
Agnieszka Piwowarczyk
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The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Views on the Absorption Rate of the European Social Fund in Romania [PDF]
Revista de Management Comparat International, 2015 Analysis of the absorption rate has a significant importance since it measures the capacity a state or region to make effective and efficient use of the funding available under cohesion policy which is considered the most important EU investment policy ...
Laura MARINAS, Eugen PRIOTEASA
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MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source