Results 101 to 110 of about 3,632,413 (364)
Molecular Oncology, EarlyView.VASP was found to be overexpressed in metastatic oral squamous cell carcinoma (OSCC) tissues. Notably, PTTG1‐ and VASP‐deficient OSCC cells demonstrated suppressed metastatic properties by disrupting the interaction between the cytoskeleton and focal adhesion (FAs) in the filopodia region.
Suyeon Park +6 more
wiley +1 more source
Scientific Reports, 2023 Despite the increasing prevalence of lean nonalcoholic fatty liver disease (NAFLD), its risk factors are not well established. We examined the association between long working hours and incident NAFLD in lean Korean workers with emphasis on sex-based ...
Ga-Young Lim +5 more
doaj +1 more source
Missing data interpolation in integrative multi-cohort analysis with disparate covariate information [PDF]
arXiv, 2022 Integrative analysis of datasets generated by multiple cohorts is a widely-used approach for increasing sample size, precision of population estimators, and generalizability of analysis results in epidemiological studies. However, often each individual cohort dataset does not have all variables of interest for an integrative analysis collected as a ...
arxiv
The Generation R Study: design and cohort update 2017
European Journal of Epidemiology, 2016 The Generation R Study is a population-based prospective cohort study from fetal life until adulthood. The study is designed to identify early environmental and genetic causes and causal pathways leading to normal and abnormal growth, development and ...
Marjolein N. Kooijman +22 more
semanticscholar +1 more source
Cohort Profile: The Nigerian HIV Geriatric Cohort Study [PDF]
BMC Public Health, 2019 Abstract Background: An estimated 280,000 adults aged 50 years and above live with HIV in Nigeria, a population set to increase with ART efficacy and expanding coverage. To learn how elderly people living with HIV (EPLHIV) in Nigeria fare, despite not being prioritized by the national treatment program, and to deepen knowledge for their ...
Patrick Dakum +11 more
openaire +4 more sources
Molecular Oncology, EarlyView.Consensus molecular subtypes (CMS1‐4) have been identified to study colorectal cancer heterogeneity and serve as potential biomarkers. In this study, we developed and evaluated NanoCMSer, a NanoString‐based classifier using 55 genes, optimized for FF and FFPE to facilitate the clinical evaluation of CMS subtyping.
Arezo Torang +10 more
wiley +1 more source
Smoking, urinary cotinine levels and incidence of visual impairment
Scientific Reports, 2021 The longitudinal relationship between smoking status and risk of developing visual impairment (VI) remains unclear. We examined the relationship of smoking status and urinary cotinine level, an objective measure of smoking, with incidence of VI.
So Young Han +4 more
doaj +1 more source
Cohort Bias Adaptation in Aggregated Datasets for Lesion Segmentation [PDF]
arXiv, 2021 Many automatic machine learning models developed for focal pathology (e.g. lesions, tumours) detection and segmentation perform well, but do not generalize as well to new patient cohorts, impeding their widespread adoption into real clinical contexts.
arxiv
Cohort profile: the Nordic Antireflux Surgery Cohort (NordASCo) [PDF]
BMJ Open, 2017 PurposeTo describe a newly created all-Nordic cohort of patients with gastro-oesophageal reflux disease (GORD), entitled the Nordic Antireflux Surgery Cohort (NordASCo), which will be used to compare participants having undergone antireflux surgery with those who have not regarding risk of cancers, other diseases and mortality.ParticipantsIncluded were
John Maret-Ouda +11 more
openaire +8 more sources
Molecular Oncology, EarlyView.The authors conducted a retrospective study of 94 patients with advanced cancer who underwent next‐generation sequencing (NGS) gene panel analysis and received targeted treatments when applicable. Results further support evidence indicating that molecular profiling provides clinical benefit.
Michaël Dang +3 more
wiley +1 more source