Results 231 to 240 of about 4,817,088 (306)

Optimal cervical cancer screening strategies for unvaccinated and HPV-vaccinated cohorts in the United States: a comprehensive comparative modeling analysis. [PDF]

Lancet Reg Health Am
de Bondt DD, Simms KT, Naslazi E, Killen J, Kim JJ, Hontelez JAC, Burger EA, Regan MC, Smith MA, Sy S, Canfell K, de Kok IMCM.   +11 more
europepmc   +1 more source

Predicting Epileptogenic Tubers in Patients With Tuberous Sclerosis Complex Using a Fusion Model Integrating Lesion Network Mapping and Machine Learning

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Accurate localization of epileptogenic tubers (ETs) in patients with tuberous sclerosis complex (TSC) is essential but challenging, as these tubers lack distinct pathological or genetic markers to differentiate them from other cortical tubers.
Tinghong Liu, Qi Wang, Suhui Kuang, Dezhi Cao, Ping Ding, Shaohui Zhang, Haihua Wei, Zhirong Wei, Jinshan Xu, Xinyu Huang, Bing Liu, Shuli Liang   +11 more
wiley   +1 more source

Multi-cohort analysis of metagenome for type 2 diabetes identified universal gut microbiota signatures across populations. [PDF]

Nutr Diabetes
Dong Y, Wang M, Zhou X, Wang P, Yan K, Wang S, Zhong JC, Li H, Zhao L, Li B, Li J.   +10 more
europepmc   +1 more source

Prognostic Implications of Sleep Architecture for Patients Admitted to the Intensive Care Unit With Status Epilepticus

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Status epilepticus (SE) is associated with significant mortality. Sleep architecture may reflect normal brain function. Impaired sleep architecture is associated with poorer outcomes in numerous conditions. Here we investigate the association of sleep architecture in continuous EEG (cEEG) with survival in SE.
Ran R. Liu, Marcus C. Ng, Gavin P. Winston, Sabrina Schaly, Garima Shukla, Lysa Boissé Lomax   +5 more
wiley   +1 more source

Radiomics-Based Assessment of Portal Hypertension Severity and Risk Stratification of Cirrhotic Patients Using Routine CT Scans. [PDF]

Liver Int
Sin C, Watzenboeck ML, Iofinova E, Balcar L, Semmler G, Scheiner B, Lampichler K, Mandorfer M, Moga L, Rautou PE, Ronot M, Menche J, Reiberger T, Scharitzer M.   +13 more
europepmc   +1 more source

In‐Depth Profiling Highlights the Effect of Efgartigimod on Peripheral Innate and Adaptive Immune Cells in Myasthenia Gravis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is an autoimmune disorder characterized by antibody‐mediated complement activation. Efgartigimod, a neonatal Fc receptor (FcRn) antagonist, is approved for treating generalized MG (gMG). However, its modulatory effects on upstream innate and adaptive immune cells remain largely unexplored.
Lei Jin, Liu Dong, Ying Wang, Dingxian He, Chong Yan, Jianying Xi, Haoqin Jiang, Yu Shi, Ming Guan, Chongbo Zhao, Jie Song, Sushan Luo   +11 more
wiley   +1 more source

Native liver survival and genetic associations in Korean patients with Alagille syndrome. [PDF]

Eur J Pediatr
Choi S, Kim DU, Kim Y, Kim L, Shim JO, Moon JS, Hahn JW, Yang HR, Chang JY, Ko JS.   +9 more
europepmc   +1 more source

Developmental, Neuroanatomical and Cellular Expression of Genes Causing Dystonia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Dystonia is one of the most common movement disorders, with variants in multiple genes identified as causative. However, an understanding of which developmental stages, brain regions, and cell types are most relevant is crucial for developing relevant disease models and therapeutics.
Darren Cameron, Nicholas E. Clifton, Daniel Cabezas de la Fuente, Peter Holmans, Nicholas J. Bray, Kathryn J. Peall   +5 more
wiley   +1 more source

Performance of PREVENT Cardiovascular Risk in Electronic Health Record-Based Clinical Practice.

JAMA Netw Open
Hong C, Niu M, Wang H, Wojdyla DM, Economou-Zavlanos N, Engelhard MM, Pignone M, Patel MR, Pencina MJ.   +8 more
europepmc   +1 more source