Results 51 to 60 of about 2,602,200 (268)

Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin, Sheila K. Pierson, Kelley C. Dacus, Mateo Sarmiento Bustamante, Saishravan Shyamsundar, Larissa Borys, Kayla McHugh, Abiola Irvine, Yoojin Jo, Adam Bagg, Mary Jo Lechowicz, Daisy Alapat, Amy Chadburn, Megan S. Lim, Gordan Srkalovic, Frits van Rhee, David C. Fajgenbaum, Joshua D. Brandstadter   +17 more
wiley   +1 more source

The Impact of the COVID‐19 Pandemic on Childhood Cancer Survival: A Population‐Based Assessment of Survival Patterns Between 2015 and 2023 in Germany

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Numerous international studies have reported declines in new cancer diagnoses, delayed diagnoses and disruptions in cancer treatment following the implementation of COVID‐19 pandemic public health measures, raising concerns that these effects may ultimately contribute to increased cancer mortality.
Friederike Erdmann, Maike Wellbrock, Javier Louro, Arndt Borkhardt, Martin Schrappe, Claudia Trübenbach, Desiree Grabow, Cécile M. Ronckers, Joachim Schüz   +8 more
wiley   +1 more source

The correlation between early or late natural menopausal age and muscle mass percentage and bone mass percentage in postmenopausal women

Zhongguo gonggong weisheng
ObjectiveTo analyze the correlation between early or late natural menopausal age and muscle mass percentage and bone mass percentage in postmenopausal women, and to provide a reference for health care of postmenopausal women.
Jiaoling LUO, Weisen ZHANG, Zhihao CHAI, Feng ZHU, Tong ZHU, Yali JIN, Jing PAN, Chaoqiang JIANG   +7 more
doaj   +1 more source

Maternal prenatal distress exposure negatively associates with the stability of neonatal frontoparietal network

Stress, 2023
Maternal prenatal distress (PD), frequently defined as in utero prenatal stress exposure (PSE) to the developing fetus, influences the developing brain and numerous associations between PSE and brain structure have been described both in neonates and in ...
Jetro J. Tuulari, Olli Rajasilta, Joana Cabral, Morten L. Kringelbach, Linnea Karlsson, Hasse Karlsson   +5 more
doaj   +1 more source

Referral Patterns and Diagnostic Timeliness in Pediatric Cancer: A Hospital‐Based Study in Indonesia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Timely diagnosis and treatment are critical for improving survival among children with cancer. In low‐ and middle‐income countries (LMICs), delays are common and may be influenced by fragmented referral pathways and diagnostic limitations.
Nur Melani Sari, Regina Hadi Putri, Fatimah Assyifa, Judith Spijkerman, Gertjan Johannes Kaspers, Susi Susanah   +5 more
wiley   +1 more source

Association of maternal leukocyte, monocyte, and neutrophil counts with hypertensive disorders of pregnancy: the Japan Environment and Children’s Study (JECS)

Scientific Reports
Hypertensive disorders of pregnancy (HDP) increase the risk of preterm births and cesarean delivery. This study aimed to investigate whether maternal blood leukocyte, monocyte, or neutrophil counts in the first trimester are related to the development of
Shiori Ishiyama, Kazuki Mochizuki, Ryoji Shinohara, Kunio Miyake, Megumi Kushima, Reiji Kojima, Sayaka Horiuchi, Sanae Otawa, Hideki Yui, Tadao Ooka, Yuka Akiyama, Hiroshi Yokomichi, Zentaro Yamagata, The Japan Environment and Children’s Study Group   +13 more
doaj   +1 more source

Birth weight changes in a major city under rapid socioeconomic transition in China

Scientific Reports, 2017
Estimates of trends in birth weight may be useful in evaluating population health. We aimed to determine whether temporal changes in birth weight have occurred amongst 2.3 million neonates born in Guangzhou, China, during 2001–2015 and investigate the ...
Jian-Rong He, Wei-Dong Li, Min-Shan Lu, Yong Guo, Fan-Fan Chan, Jin-Hua Lu, Li-Fang Zhang, Song-Ying Shen, Xiao-Yan Xia, Ping Wang, Wei-Jian Mo, Kin Bong Hubert Lam, Jane E. Hirst, Hui-Min Xia, Xiu Qiu   +14 more
doaj   +1 more source

Improving the efficiency of reactive case detection for malaria elimination in southern Zambia: a cross-sectional study

Malaria Journal, 2020
Background Reactive case detection (RCD) seeks to enhance malaria surveillance and control by identifying and treating parasitaemic individuals residing near index cases.
Fiona R. P. Bhondoekhan, Kelly M. Searle, Harry Hamapumbu, Mukuma Lubinda, Japhet Matoba, Michael Musonda, Ben Katowa, Timothy M. Shields, Tamaki Kobayashi, Douglas E. Norris, Frank C. Curriero, Jennifer C. Stevenson, Philip E. Thuma, William J. Moss, for the Southern and Central Africa International Centers of Excellence for Malaria Research   +14 more
doaj   +1 more source

Low intake of β carotene and dietary fiber from vegetables and fruits in patients with chronic kidney disease

Scientific Reports, 2022
Patients with chronic kidney disease (CKD) occasionally need to restrict their consumption of vegetables and fruits. However, recent evidence suggests that plant-based diets have beneficial effects in patients with CKD.
Toshiaki Nakano, Shigeru Tanaka, Kazuhiko Tsuruya, Takanari Kitazono   +3 more
doaj   +1 more source

Venetoclax‐Based Therapy as a Bridge to Hematopoietic Stem Cell Transplantation in Relapsed or Refractory Pediatric Acute Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Relapsed and/or refractory (R/R) pediatric acute leukemia carries a dismal prognosis, largely driven by chemoresistance to conventional salvage therapy. The BH3‐mimetic venetoclax, combined with chemotherapy or hypomethylating agents, has demonstrated efficacy in small clinical trials.
Katherine S. Colman, Deborah Meyran, Vajiranee Malalasekera, Heather Weerdenburg, Janine Campbell, Rachel Conyers, Stacie Wang, Hannah Walker, Seong Lin Khaw, Diane Hanna   +9 more
wiley   +1 more source