Molecular Oncology, EarlyView.This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan +8 more
wiley +1 more source
Results of risk of bias assessment for cohort studies using JBI checklist for cohort Studies.
Results of risk of bias assessment for cohort studies using JBI checklist for cohort Studies.
Eslavath Rajkumar (10507295) +6 more
core +1 more source
Lessons from Cohort Studies of Targetable Metabolic Deficiencies in Lung Cancer. [PDF]
Clin Cancer ResLi D, Garon EB.
europepmc +1 more source
Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma
Molecular Oncology, EarlyView.Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara +10 more
wiley +1 more source
Diagnosing Diabetes in Cohort Studies: The Case for Comprehensive Glycemic Assessment. [PDF]
Geriatr Gerontol IntQiu C, Du H.
europepmc +1 more source
USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival
Molecular Oncology, EarlyView.CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna +8 more
wiley +1 more source
1970 British Cohort Study: Age 16, Sweep 4 Head Teacher Questionnaire, 1986
, 2005 copyright UK Data Service and data collection copyright owner.The 1970 British Cohort Study (BCS70) is a longitudinal birth cohort study, following a nationally representative sample of over 17,000 people born in England, Scotland and Wales in a single ...
University of London, Institute of Education, Centre for Longitudinal Studies
core
Evidence for a dose-response association of hyperuricemia with stroke incidence: a meta-analysis of cohort studies. [PDF]
Front NeurolLiu Y, Wang J, Bai S, Ji H.
europepmc +1 more source
Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer
Molecular Oncology, EarlyView.New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau +9 more
wiley +1 more source
copyright UK Data Service and data collection copyright owner.The Harmonised Data in Five National Longitudinal Cohort Studies project, supported by the Economic and Social Research Council (ESRC), brings together data from five British cohort ...
University College London, UCL Institute of Education, Centre for Longitudinal Studies
core +1 more source