Results 251 to 260 of about 3,695,194 (322)

Systemic T Cell Receptor Profiling Reveals Adaptive Immune Activation and Potential Immune Signatures of Diagnosis and Brain Atrophy in Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epilepsy is increasingly associated with immune dysregulation and inflammation. The T cell receptor (TCR), a key mediator of adaptive immunity, shows repertoire alterations in various immune‐mediated diseases. The unique TCR sequence serves as a molecular barcode for T cells, and clonal expansion accompanied by reduced overall TCR ...
Yong‐Won Shin, Sang Bin Hong, Yong Woo Shin, Inpyeong Hwang, Jaeseong Oh, Jihyeon Choi, Narae Kim, Jangsup Moon, Keun‐Hwa Jung, Kyung‐Il Park, Ki‐Young Jung, Kon Chu, Sang Kun Lee   +12 more
wiley   +1 more source

IQ in childhood and atherosclerosis in middle-age: 40 Year follow-up of the Newcastle Thousand Families Cohort Study

, 2013
Beverly Roberts, G. David Batty, Catharine R. Galé, Ian J. Deary, Louise Parker, Mark S. Pearce   +5 more
openalex   +2 more sources

Interleukin‐6 as a Key Biomarker in Facioscapulohumeral Dystrophy: Evidence From Longitudinal Analyses

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy type 1 (FSHD1) is a progressive neuromuscular disorder with no approved treatments. Identifying reliable biomarkers is critical to monitor disease severity, activity, and progression. Interleukin‐6 (IL‐6) has been proposed as a candidate biomarker, but longitudinal validation is limited ...
Jonathan Pini, Emanuela Martinuzzi, Sandra Dhifallah, Abderhmane Slioui, Angela Puma, Luisa Villa, Michele Cavalli, Andra Ezaru, Jérémy Garcia, Manuela Gambella, Federico Torre, Luca Jacopo Pavan, Nicolas Glaichenhaus, Sabrina Sacconi   +13 more
wiley   +1 more source

Changes in accelerated aging and risk of cardiovascular disease and mortality: three cohort studies. [PDF]

BMC Med
Zhang JJ, Yu HC, Geng TT, Chen SH, Wang YX, Guo H, Zhang XM, He MA, Gao JL, Liu G, Liao YF, Wu SL, Pan A.   +12 more
europepmc   +1 more source

Postoperative Outcomes Within Enhanced Recovery After Surgery Protocol in Elective Total Hip and Knee Arthroplasty. POWER.2 Study: Study Protocol for a Prospective, Multicentre, Observational Cohort Study

, 2019
Javier Ripollés‐Melchor, Ane Abad‐Motos, Margarita Logroño-Egea, César Aldecoa, José Antonio García‐Erce, Ignacio Jiménez, C. Cassinello, Óliver Marín-Peña, Carlos Ferrando-Ortolá, Alejandro Suárez-de-la-Rica, Manuel Ángel Gómez‐Ríos, Rubén Sánchez-Martín, Alfredo Abad‐Gurumeta, R. Casans‐Francés, Ana Mugarra-Llopis, Marina Varela-Durán, J. Longás Valién, Álvaro Ramiro-Ruiz, Ana Cuellar-Martínez, José Manuel ́Ramírez Rodríguez, J.M. Calvo Vecino, Jose M. Ramirez-Rodriguez, Jose M. Calvo-Vecino   +22 more
openalex   +1 more source

Relapsing–Remitting Multiple Sclerosis Is Associated With a Dysbiotic Oral Microbiome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Multiple sclerosis (MS) is a chronic autoimmune disorder characterized by inflammation, demyelination, and neurological impairment. While the gut microbiota's role in MS is extensively studied, the association between the oral microbiota and MS remains underexplored, particularly in North American cohorts.
Sukirth M. Ganesan, Meeta Yadav, Sudeep Ghimire, Peter C. Lehman, Apurva J. Patel, Sydney Woods, Heena Olalde, Jemmie Hoang, Mishelle Paullus, Catherine Cherwin, Christine Gill, Tracey Cho, Ashutosh K. Mangalam   +12 more
wiley   +1 more source

Quantifying the impact of biobanks and cohort studies. [PDF]

Proc Natl Acad Sci U S A
Dorantes-Gilardi R, Ivey KL, Costa L, Matty R, Cho K, Gaziano JM, Barabási AL.   +6 more
europepmc   +1 more source

Prediction Model for Etiologic Differentiation of Isolated Vestibular Syndrome in Emergency Settings

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to develop and validate a predictive model for differentiating central from peripheral etiologies in patients with isolated vestibular syndrome (VS). Methods In this multicenter retrospective cohort study, 506 patients with isolated VS from five hospitals were divided into derivation (n = 301) and validation (n = 205)
Guo Wenting, Du Liping, Yang Yi, Hu Jin, Ye Bijun, Wang Jianer, Liu Shuangsi, Guo Shunyuan, Cai Xiaofeng, Wang Huiyuan, Wu Bin, Yu Xiang, Shi Tianming   +12 more
wiley   +1 more source

Associations of common infections with frailty and mortality in two UK cohort studies

Smeeth D, Warren-Gash C, Green RE, Butt J, Waterboer T, Hughes AD, Chaturvedi N, Williams DM.   +7 more
europepmc   +1 more source

Sleep trajectories and osteoporosis incidence: findings from two prospective cohort studies. [PDF]

Front Public Health
Zhang X, Li Z, Tian H, Lv T, Shang J, Cai E.   +5 more
europepmc   +1 more source