Results 301 to 310 of about 43,381,677 (339)

A Novel C19orf47‐AKT2 Chimeric RNA Generated by Cis‐Splicing of Adjacent Genes Is Associated With Glioblastoma Prognosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Malignant gliomas pose significant therapeutic challenges. This study aimed to identify and characterize a novel chimeric RNA in glioma and assess its clinical and functional significance for precision treatment. Methods The C19orf47‐AKT2 chimeric RNAs were identified through RNA sequencing and validated by polymerase chain reaction.
Zihan Wang, Bowen Ni, Kezhi Wu, Qi Zhang, Jinglin Guo, Runwei Yang, Ziyu Wang, Guozhong Yi, Guanglong Huang, Minyi He, Yimin Xu, Yawei Liu   +11 more
wiley   +1 more source

An International Research Agenda for Oral Health Birth Cohort Studies. [PDF]

J Dent Res
Peres KG, Kalhan AC, Sarawagi S, Peres MA, Feldens CA, Chaffee BW, Barros AJD, Rugg-Gunn A, Nascimento GG.   +8 more
europepmc   +1 more source

In Vitro Modeling of Natural Killer Cell Cytotoxicity to Inform Personalized ALS Therapeutics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Natural killer (NK) cells might contribute to motor neuron death in amyotrophic lateral sclerosis (ALS) through direct cytotoxicity, a process that could be inhibited with the FDA‐approved JAK/STAT pathway inhibitor, tofacitinib. This study aimed to verify that tofacitinib can suppress NK cell cytotoxicity, investigate if immune cell
Benjamin J. Murdock, Jihyun Park, Dae‐Gyu Jang, Bangyao Zhao, Samuel J. Teener, Ian F. Webber‐Davis, Lili Zhao, Eva L. Feldman, Stephen A. Goutman   +8 more
wiley   +1 more source

A protocol for three observational cohort studies evaluating adverse outcomes, excess costs and repeat procedures after surgery for breast cancer in the USA. [PDF]

J Comp Eff Res
Wing SE, Liu Y, Johnson JC, Moore KJ, Zheng F.   +4 more
europepmc   +1 more source

Asthma and the risk of cardiovascular diseases and mortality: a meta-analysis of cohort studies. [PDF]

Ther Adv Respir Dis
Jiang Y, Huang X, Yu D, Xu C, Wang Y, Wang X, Shen Y.   +6 more
europepmc   +1 more source

The role of statins in dementia or Alzheimer's disease incidence: a systematic review and meta-analysis of cohort studies. [PDF]

Front Pharmacol
Du Y, Yu Z, Li C, Zhang Y, Xu B.
europepmc   +1 more source

Mental healthcare utilisation among individuals with colorectal cancer: population-based cohort studies. [PDF]

BMJ Oncol
Cheng V, Sayre EC, Cheng V, Loree JM, Gill S, Murphy RA, Howren A, De Vera MA.   +7 more
europepmc   +1 more source

Association of antioxidants intake in diet and supplements with risk of Alzheimer's disease: a systematic review and dose-response meta-analysis of prospective cohort studies. [PDF]

Aging Clin Exp Res
Hu X, Zhou J, Sun Y, Wang Z.
europepmc   +1 more source