Results 51 to 60 of about 3,374,176 (336)

Outcomes in Cohort Studies [PDF]

Epidemiologic Reviews, 1998
The initial intellectual appeal of the cohort design for epidemiologic studies stems from the obvious fact that the method of subject selection leaves little doubt about the temporal relation between the exposure and the disease whose relation is under study.
openaire   +3 more sources

Psychosocial twin cohort studies in Japan: the Keio Twin Research Center (KoTReC) [PDF]

, 2019
The Keio Twin Research Center (KoTReC) was established in 2009 at Keio University to combine two longitudinal cohort projects — the Keio Twin Study (KTS) for adolescence and adulthood and the Tokyo Twin Cohort Project (ToTCoP) for infancy and childhood ...
Ando, Juko, Deno, Minako, Fujisawa, Keiko, K., Hiraishi, Kai, Kawamoto, Tetsuya, Kijima, Nobuhiko, Kobayashi, Kazuhiro, Murayama, Kou, Nozaki, Mari, Okada, Mitsuhiro, Ozaki, Koken, Sakagami, Masamichi, Sasaki, Shoko, Shikishima, Chizuru, Someya, Yoshiaki, Suzuki, Kunitake, Takahashi, Yusuke, Takizawa, Ryu, Tanaka, Mami, Toda, Tatsushi, Yamagata, Shinji   +20 more
core   +2 more sources

Single‐cell insights into the role of T cells in B‐cell malignancies

FEBS Letters, EarlyView.
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley   +1 more source

Evaluation of In-Hospital Management for Febrile Illness\ud in Northern Tanzania before and after 2010 World Health\ud Organization Guidelines for the Treatment of Malaria [PDF]

, 2014
In 2010, the World Health Organization (WHO) published updated guidelines emphasizing and expanding recommendations for a parasitological confirmation of malaria before treating with antimalarials. This study aimed to assess differences in historic (2007–
Biggs, Holly M., Crump, John A., Maro, Venace P., Moon, Andrew M., Reddy, Elizabeth A., Rubach, Matthew P., Saganda, Wilbrod   +6 more
core   +3 more sources

Unlocking the potential of tumor‐derived DNA in urine for cancer detection: methodological challenges and opportunities

Molecular Oncology, EarlyView.
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever, Renske D. M. Steenbergen   +1 more
wiley   +1 more source

The relation between cholesterol and haemorrhagic or ischaemic stroke in the Renfrew/Paisley study [PDF]

, 2000
Studies have found little association between cholesterol and overall stroke risk, but this could be attributable to different relations for haemorrhagic and ischaemic stroke.
Ben-Shlomo, Y., C. L Hart, Hart, C., Hawthorne, V.M., Rodgers, A.   +4 more
core   +2 more sources

Identification of functional and diverse circulating cancer‐associated fibroblasts in metastatic castration‐naïve prostate cancer patients

Molecular Oncology, EarlyView.
Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink, Leon W. M. M. Terstappen, Eshwari Dathathri, Khrystany Isebia, Jaco Kraan, John Martens, Ruchi Bansal   +6 more
wiley   +1 more source

Gestational weight gain and group prenatal care: A systematic review and meta-analysis [PDF]

, 2019
Background Group visits for chronic medical conditions in non-pregnant populations have demonstrated successful outcomes including greater weight loss compared to individual visits for weight management.
AA Mamun, Adam K. Lewkowitz, AG Tsai, B Hill, B Muktabhant, BE O'Donnell, C Klima, D Edelman, D Moher, DA Renjilian, DE Clancy, DR Black, E Oken, E Oken, E Ruiz-Mirazo, EB Carter, Ebony Carter, EE Tanner-Smith, G Trotman, HM Holbrook, HP Kennedy, Institute of Medicine, J Brumley, J Sheeder, JR Ickovics, LA Gilmore, LF Stead, M Kotelchuck, MA Kominiarek, MA Kominiarek, Melissa Simon, Michelle A. Kominiarek, MM Schellinger, NP Deputy, R Zielinski, RB Walton, RE Burke, S Heshka, S Phelan, S Phelan, S Rising, SE Mazzoni, SH Downs, SM Brokaw, SM Harden, SR O'Connor, Susan A. Fowler, TE Trudnak, U Magriples, V Paul-Ebhohimhen, W Wolfe, WC Knowler   +51 more
core   +2 more sources

Cohort Profile: the Jerusalem longitudinal cohort study [PDF]

International Journal of Epidemiology, 2008
Whilst it has been suggested that about 25% of the variability in human longevity is attributed to genetic influences, the remaining 75% is consequent upon a complex interplay of biological, environmental, social and culturally determined factors. In rising to the challenge of understanding the complexities of human ageing, a valuable tool to emerge in
Eliana Ein-Mor, Jochanan Stessman, Michael Bursztyn, Daniel Azoulay, Jeremy M. Jacobs, Aaron Cohen   +5 more
openaire   +3 more sources

Clinical applications of next‐generation sequencing‐based ctDNA analyses in breast cancer: defining treatment targets and dynamic changes during disease progression

Molecular Oncology, EarlyView.
Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker, Samantha Hasenleithner, Rupert Bartsch, Simon P. Gampenrieder, Daniel Egle, Christian F. Singer, Gabriel Rinnerthaler, Michael Hubalek, Katja Schmitz, Zsuzsanna Bago‐Horvath, Andreas Petzer, Sonja Heibl, Ellen Heitzer, Marija Balic, Michael Gnant   +14 more
wiley   +1 more source