Results 171 to 180 of about 45,438,228 (409)

Molecular and functional profiling unravels targetable vulnerabilities in colorectal cancer

Molecular Oncology, EarlyView.
We used whole exome and RNA‐sequencing to profile divergent genomic and transcriptomic landscapes of microsatellite stable (MSS) and microsatellite instable (MSI) colorectal cancer. Alterations were classified using a computational score for integrative cancer variant annotation and prioritization.
Efstathios‐Iason Vlachavas, Konstantinos Voutetakis, Vivian Kosmidou, Spyridon Tsikalakis, Spyridon Roditis, Konstantinos Pateas, Ryangguk Kim, Kymberleigh Pagel, Stephan Wolf, Gregor Warsow, Antonia Dimitrakopoulou‐Strauss, Georgios N. Zografos, Alexander Pintzas, Johannes Betge, Olga Papadodima, Stefan Wiemann   +15 more
wiley   +1 more source

Antibiotherapy with and without bone debridement in diabetic foot osteomyelitis: a retrospective cohort study [PDF]

, 1969
Asım Ülçay, Ahmet Karakaş, Mesut Mutluoğlu, Günalp Uzun, Vedat Turhan, Hakan Ay   +5 more
openalex   +1 more source

Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study

The Lancet, 2020
F. Zhou, Ting Yu, R. Du, Guohui Fan, Y. Liu, Zhibo Liu, J. Xiang, Ye-ming Wang, Bin Song, Xiaoying Gu, Lulu Guan, Yuan Wei, Hui Li, Xudong Wu, Jiuyang Xu, Shengjin Tu, Yi Zhang, Hua Chen, B. Cao   +18 more
semanticscholar   +1 more source

Multiplex single‐cell profiling of putative cancer stem cell markers ALDH1, SOX9, SOX2, CD44, CD133 and CD15 in endometrial cancer

Molecular Oncology, EarlyView.
Cancer stem cells are associated with aggressive disease, but a deep characterization of such markers is lacking in endometrial cancer. This study uses imaging mass cytometry to explore putative cancer stem cell markers in endometrial tumors and corresponding organoid models.
Hilde E. Lien, Marta E. Hjelmeland, Hege F. Berg, Rose M. Gold, Kathrine Woie, Lars A. Akslen, Ingfrid S. Haldorsen, Camilla Krakstad   +7 more
wiley   +1 more source

Serum phosphate level at initiation of dialysis is associated with all-cause mortality: a multicenter prospective cohort study

Renal Failure, 2018
Introduction: As glomerular filtration rate (GFR) decreases, serum phosphate level increases. Previous reports indicated that serum phosphate level was associated with mortality in patients on dialysis.
Akiko Owaki, Daijo Inaguma, Isao Aoyama, Shinichiro Inaba, Shigehisa Koide, Eri Ito, Kazuo Takahashi, Hiroki Hayashi, Midori Hasegawa, Yukio Yuzawa, AICOPP group   +10 more
doaj   +1 more source

Leveraging Foundation Language Models (FLMs) for Automated Cohort Extraction from Large EHR Databases [PDF]

arXiv
A crucial step in cohort studies is to extract the required cohort from one or more study datasets. This step is time-consuming, especially when a researcher is presented with a dataset that they have not previously worked with. When the cohort has to be extracted from multiple datasets, cohort extraction can be extremely laborious.
arxiv  

1-year outcomes in hospital survivors with COVID-19: a longitudinal cohort study

The Lancet, 2021
Lixue Huang, Q. Yao, Xiaoying Gu, Qiongya Wang, L. Ren, Ye-ming Wang, Ping-an Hu, Li Guo, Min Liu, Jiuyang Xu, Xueyang Zhang, Yali Qu, Yanqing Fan, Xia Li, Caihong Li, Ting Yu, Jia’an Xia, Ming-fen Wei, Li Chen, Yanping Li, F. Xiao, Dan Liu, Jianwei Wang, Xianguang Wang, B. Cao   +24 more
semanticscholar   +1 more source

GROWING UP IN IRELAND. Cohort '08 (Infant Cohort). Design, Instrumentation and Procedures for Cohort ’08 of Growing Up in Ireland at 9 Years Old (Wave 5) [PDF]

, 2019
Growing Up in Ireland is the national longitudinal cohort study of children that commenced in 2006. The study has followed two groups of Irish children: Cohort ’98 (so-called because most of them were born in 1998; formerly called the ‘Child Cohort ...
McNamara, Eoin, Murray, Aisling, O'Mahony, Desmond   +2 more
core  

Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression

Molecular Oncology, EarlyView.
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park, Jae Won Oh, Hyewon Chung, Jung Won Kwon, Yi Rang Na, Kwang Pyo Kim, Seung Hyeok Seok   +6 more
wiley   +1 more source

A Novel Approach for Manual Segmentation of the Amygdala and Hippocampus in Neonate MRI

Frontiers in Neuroscience, 2019
The gross anatomy of the infant brain at term is fairly similar to that of the adult brain, but structures are immature, and the brain undergoes rapid growth during the first 2 years of life.
Niloofar Hashempour, Niloofar Hashempour, Jetro J. Tuulari, Jetro J. Tuulari, Jetro J. Tuulari, Harri Merisaari, Kristian Lidauer, Iiris Luukkonen, Jani Saunavaara, Riitta Parkkola, Tuire Lähdesmäki, Satu J. Lehtola, Maria Keskinen, John D. Lewis, Noora M. Scheinin, Noora M. Scheinin, Noora M. Scheinin, Linnea Karlsson, Linnea Karlsson, Hasse Karlsson, Hasse Karlsson   +20 more
doaj   +1 more source