Results 181 to 190 of about 46,993,701 (406)

An outbreak of severe Kawasaki-like disease at the Italian epicentre of the SARS-CoV-2 epidemic: an observational cohort study

The Lancet, 2020
L. Verdoni, A. Mazza, A. Gervasoni, L. Martelli, M. Ruggeri, M. Ciuffreda, E. Bonanomi, L. D’Antiga   +7 more
semanticscholar   +1 more source

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

FEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee, Jung Yoon Ho, In Sun Hwang, Youn Jin Choi   +3 more
wiley   +1 more source

Association of Social Isolation and Loneliness With Incident Heart Failure in a Population-Based Cohort Study

, 2023
Yannis Yan Liang, Yilin Chen, Hongliang Feng, Xiangxin Liu, Qi Yong H. Ai, Huachen Xue, Xinyue Shu, Foqian Weng, Zhixuan He, Jiacheng Ma, Huan Ma, Sizhi Ai, Qingshan Geng, Jihui Zhang   +13 more
openalex   +2 more sources

Association between social capital and mental health among older people living with HIV: the Sichuan Older HIV-Infected Cohort Study (SOHICS) [PDF]

, 2020
Jiayu Han, Peng Jia, Yuling Huang, Bo Gao, Bin Yu, Shifan Yang, Jun Yu, Jun Xiong, Chang Liu, Tian Xie, Peijie Dong, Chao Yang, Zixin Wang, Shujuan Yang   +13 more
openalex   +1 more source

Coronavirus disease 2019 vaccine response in pregnant and lactating women: a cohort study

American Journal of Obstetrics and Gynecology, 2021
K. Gray, E. Bordt, C. Atyeo, Elizabeth A. DeRiso, B. Akinwunmi, Nicola Young, Aranxta Medina Baez, L. Shook, D. Cvrk, K. James, R. D. De Guzman, S. Brigida, K. Diouf, I. Goldfarb, Lisa M. Bebell, L. Yonker, A. Fasano, Sayed A. Rabi, M. Elovitz, G. Alter, A. Edlow   +20 more
semanticscholar   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Millennium Cohort Study Second Survey: A User's Guide to Initial Findings [PDF]

, 2007
This report presents some of the main initial findings of the Second Survey of the Millennium Cohort Study conducted by the Centre for Longitudinal Studies, which is based at the Institute of Education, University of London.
Hansen, Kirstine, Joshi, Heather
core   +1 more source

An exploration of the dynamic longitudinal relationship between mental health and alcohol consumption: a prospective cohort study [PDF]

, 2014
Steven Bell, Annie Britton
openalex   +1 more source

Epidemiology and transmission of COVID-19 in 391 cases and 1286 of their close contacts in Shenzhen, China: a retrospective cohort study

Lancet. Infectious Diseases (Print), 2020
Qifang Bi, Yongsheng Wu, S. Mei, Chenfei Ye, X. Zou, Zhen Zhang, Xiaojian Liu, Lan Wei, S. Truelove, Tong Zhang, Wei Gao, Cong Cheng, Xiujuan Tang, Xiaoliang Wu, Yu Wu, B. Sun, Suli Huang, Yu Sun, Juncen Zhang, Ting Ma, J. Lessler, T. Feng   +21 more
semanticscholar   +1 more source

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source