Results 181 to 190 of about 45,541,444 (388)
Clinical impact of COVID-19 on patients with cancer (CCC19): a cohort study
The Lancet, 2020 N. Kuderer, T. Choueiri, D. Shah, Y. Shyr, S. Rubinstein, D. Rivera, S. Shete, Chih-Yuan Hsu, A. Desai, Gilberto Lopes, P. Grivas, P. Grivas, C. Painter, S. Peters, M. Thompson, Z. Bakouny, G. Batist, T. Bekaii-Saab, M. Bilen, N. Bouganim, M. B. Larroya, D. Castellano, S. Prete, D. Doroshow, P. Egan, A. Elkrief, D. Farmakiotis, D. Flora, M. Galsky, M. Glover, E. Griffiths, A. Gulati, Shilpa Gupta, Navid Hafez, T. Halfdanarson, J. Hawley, E. Hsu, A. Kasi, A. Khaki, A. Khaki, Christopher A. Lemmon, C. Lewis, Barbara B. Logan, T. Masters, R. McKay, R. Mesa, A. Morgans, M. Mulcahy, O. Panagiotou, P. Peddi, N. Pennell, K. Reynolds, Lane R. Rosen, R. Rosovsky, M. Salazar, A. Schmidt, Sumit A Shah, J. Shaya, J. Steinharter, K. Stockerl-Goldstein, S. Subbiah, D. Vinh, F. Wehbe, L. Weissmann, J. Wu, E. Wulff-Burchfield, Zhuoer Xie, Albert C. Yeh, Albert C. Yeh, P. Yu, A. Zhou, L. Zubiri, S. Mishra, G. Lyman, G. Lyman, B. Rini, J. Warner, M. Abidi, J. Acoba, Neeraj Agarwal, S. A. Ahmad, Archana Ajmera, Jessica Altman, Anne H. Angevine, Nilo Azad, Michael H. Bar, Aditya Bardia, Jill S. Barnholtz-Sloan, Briana Barrow, B. Bashir, Rimma Belenkaya, S. Berg, E. Bernicker, C. Bestvina, R. Bishnoi, Genevieve Marie Boland, Mark Bonnen, G. Bouchard, Daniel W. Bowles, F. Busser, A. Cabal, P. Caimi, Theresa M. Carducci, C. Casulo, James L. Chen, J. Clement, D. Chism, Erin Cook, C. Curran, Ahmad Daher, Mark Dailey, S. Dahiya, John Deeken, G. Demetri, Sandy DiLullo, N. Duma, Rawad Elias, B. Faller, L. Fecher, Lawrence E. Feldman, C. Friese, Paul Fu, Julie Fu, A. Futreal, J. Gainor, Jorge E Garcia, David M. Gill, E. Gillaspie, Antonio Giordano, Grace Glace, Axel Grothey, S. Gulati, M. Gurley, B. Halmos, Roy S. Herbst, D. Hershman, Kent Hoskins, R. Jain, Salma K. Jabbour, Alokkumar Jha, Douglas B. Johnson, Monika Joshi, K. Kelleher, J. Kharofa, H. Khan, J. Knoble, V. Koshkin, Amit A. Kulkarni, P. Lammers, J. Leighton, Mark A. Lewis, Xuanyi Li, Ang Li, K. M. Lo, A. Loaiza-Bonilla, Patricia LoRusso, C. Low, M. Lustberg, D. Mahadevan, Abdul-Hai Mansoor, Michelle Marcum, M. Markham, C. Marshall, Sandeep H. Mashru, Sara Matar, C. McNair, Shannon K. McWeeney, J. Mehnert, A. Menendez, H. Menon, M. Messmer, Ryan S. Monahan, Sarah Mushtaq, G. Nagaraj, Sarah Nagle, J. Naidoo, John M. Nakayama, Vikram M. Narayan, Heather H. Nelson, Eneida R. Nemecek, R. Nguyen, P. Nuzzo, P. Oberstein, A. Olszewski, Susie Owenby, M. Pasquinelli, John Philip, Sabitha Prabhakaran, M. Puc, Amelie G. Ramírez, J. Rathmann, S. Revankar, Young Soo Rho, Terence D. Rhodes, Robert L. Rice, Gregory Riely, J. Riess, Cameron Rink, E. Robilotti, Lori J. Rosenstein, B. Routy, M. Rovito, M. W. Saif, Amit Sanyal, L. Schapira, C. Schwartz, Oscar K. Serrano, Mansi Shah, Chintan Shah, Grace Shaw, A. Shergill, Geoffrey P. Shouse, Heloisa P. Soares, Carmen C. Solorzano, Pramod K. Srivastava, Karen Stauffer, D. Stover, Jamie Stratton, Catherine Stratton, V. Subbiah, R. Tamimi, N. Tannir, U. Topaloglu, E. V. Allen, S. V. Loon, Karen Vega-Luna, N. Venepalli, Amit Verma, Praveen Vikas, Sarah Wall, P. L. Weinstein, Matthias Weiss, T. Wise-Draper, William A. Wood, Wenxin Xu, S. Yackzan, R. Zacks, Tian Zhang, Andrea J. Zimmer, Jack West +239 moresemanticscholar +1 more sourceThe subcellular distribution of phosphorylated Y‐box‐binding protein‐1 at S102 in colorectal cancer patients, stratified by KRAS mutational status and clinicopathological features
Molecular Oncology, EarlyView.This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...Konstanze Lettau, Stephan Forchhammer, Birgit Fehrenbacher, Lejla Mahmutovic, Marcus Scharpf, Gunnar Blumenstock, Martin Schaller, Irina Bonzheim, Shayan Khozooei, Mahmoud Toulany +9 morewiley +1 more sourceMortality and pulmonary complications in patients undergoing surgery with perioperative SARS-CoV-2 infection: an international cohort study
The Lancet, 2020 D. Nepogodiev, J. Glasbey, E. Li, O. Omar, J. Simoes, T. Abbott, Osaid Alser, MD, MSc (Oxon), A. Arnaud, B. Bankhead-Kendall, K. Breen, M. Cunha, G. Davidson, S. di Saverio, G. Gallo, E. Griffiths, R. Gujjuri, P. Hutchinson, H. Kaafarani, H. Lederhuber, M. Löffler, H. Mashbari, A. Minaya‐Bravo, D. Morton, D. Moszkowicz, F. Pata, G. Tsoulfas, M. Venn, A. Bhangu, D. Cox, A. Roslani, F. Alakaloko, J. D. de Vries, M. A. Aaraj, S. Abbott, M. Abdalla, A. Abdelaal, A. Ademuyiwa, T. Aherne, O. Ali, G. Alkadeeki, A. C. Almeida, M. Alrahawy, G. Ambler, E. Alameer, S. Andreani, B. de Andrés-Asenjo, L. L. Antoñanzas, S. Aoun, F. Ashoush, K. Augestad, R. Avellana, F. Ayeni, J. Ayorinde, B. Babu, M. Baig, O. Bajomo, O. Baker, M. Baker, A. Baldwin, V. Ban, R. Baron, A. G. Barranquero, C. Barry, A. Di bartolomeo, Gary Alan Bass, M. Bath, H. Batjer, A. Beamish, A. Belgaumkar, M. Bence, R. Benson, J. C. Bernal-Sprekelsen, A. Bhama, A. Bhavaraju, W. Biffl, C. Blundell, A. Boddy, A. Borgstein, D. Bosanquet, K. Bosch, A. Bouhuwaish, M. Bozkurt, Collin E. M. Brathwaite, B. Brown, Oliver D Brown, Allison Brown, I. Buarque, A. Bueno-Cañones, M. Bulugma, J. Burke, M. Byrne, Elima P Cagigal-Ortega, R. Callcut, F. Di Candido, M. Canova, W. Carlos, E. Caruana, L. Cato, A. Catton, A. P. Ceretti, T. Chase, F. Chiara, A. Chowdhury, E. Chung, P. Cicerchia, E. Clough, Natasha L Coleman, C. Collins, M. Collins, E. Colonna, L. Comini, T. Connolly, P. Coughlin, Laura Fernández-Gomez Cruzado, B. Davidson, R. Davies, E. Davies, Niall F. Davis, B. E. Dawson, Benjamin John Floyd Dean, M. G. Delgado, J. Diaz, K. Dickson, M. Díez-Alonso, J. R. Dixon, M. Doe, T. Drake, F. T. Drake, J. Duffy, D. Dunne, N. Dunne, V. Durán-Muñoz-Cruzado, A. Durst, N. Eardley, J. Edwards, A. Elfallal, M. Elfiky, J. Elliott, S. Emile, K. Emslie, F. Endorf, J. Engel, D. Enjuto, E. Etchill, J. Evans, B. Fahey, C. Faria, C. Feo, H. Ferguson, B. Fernandez, Andrés G. Fernández, Antonio J. Fernández, Borja Camacho Fernández-Pacheco, J. Fitzgerald, G. B. Fonsi, Roser Farré Font, A. Fowler, G. Franco, Kenneth R. Fretwell, Lorena Sanchon Fructuoso, G. Fusai, Miguel Teodoro Hernandez Garcia, M. Garcia-Urena, C. Gill, S. Gisbertz, R. Del Giudice, M. Giuffrida, M. Di Giuseppe, Maria F. Gomez, J. González, C. Guariglia, A. Hainsworth, Bria J. Hall, J. R. Hall, J. Hammond, M. Haqqani, E. Harrison, J. Hazelton, M. van Heinsbergen, A. Hill, C. Hing, S. Hirji, M. W. Ho, C. Holbrook, T. Holme, James C. Hopkins, D. Hopkinson, F. Hossain, V. Hudson, J. Hughes, E. Hwang, M. Ibrahim, Simone M. Isolani, P. Jara, M. Jenkinson, H. Jenny, D. Jeyaretna, R. Jones, Andrew P. Jones, P. Jonker, M. Jönsson, D. Joyce, K. Kalkwarf, S. Kamarajah, M. El kassas, D. Kavanagh, J. Keatley, M. Khalefa, J. Khan, B. Kirmani, A. Kisiel, S. Kouris, M. Kowal, P. Labib, J. Larkin, J. Lauscher, W. Leclercq, Frances Ledesma, A. Leite-Moreira, E. Leung, S. Lewis, M. J. Lima, Daniel J. Lin, Helen Liu, A. Lowery, Saida Martel Lozano, C. Luney, Mariana Maia, N. Mariani, M. Marino, A. Marra, C. Marsh, R. Martin, S. McCluney, R. McIntyre, S. Mckay, K. McKevitt, A. Meagher, M. Mehdi, B. Mehigan, Melania Gonzalez-De Miguel, M. De Miguel-Ardevines, Carlos San Miguel-Méndez, S. Mills, H. Mohan, J. Moir, J. Monson, J. Monteiro, M. T. Montella, C. Montesinos, M. Morgom, F. Moura, J. Muguerza, S. Murphy, P. De Nardi, D. Naumann, P. Neary, D. Neely, J. Ng-Kamstra, A. Ngu, T. Nguyen, G. Niță, Q. Nunes, R. Nygaard, L. O'Meara, J. R. O'Neill, B. Okafor, S. Olson, A. Oo, P. C. Ormazabal, A. Osorio, M. Pachl, J. Parry, P. Patel, D. D. Pérez, C. Pérez, L. E. Pérez-Sánchez, Ana Nogués Pevidal, A. P. Pezzuto, M. Philp, T. Pinkney, J. Pollok, M. Povey, A. A. Poza, A. Rajgor, J. Rao, D. Raptis, H. Rice, P. Ridgway, A. Rivas, J. C. Rodríguez-Sanjuán, L. Rogers, A. Da Roit, R. Rollett, J. L. Romera, S. Rooney, V. Roxo, B. Le Roy, E. Rubio, C. Ruiz, Manuel Losada Ruiz, É. Ryan, Abdel Rahman Saad, S. Saeed, Hiba A Salama, Abdulrauf A Salamah, María Gutiérrez Samaniego, G. Sampietro, D. Sarma, K. Schaffer, A. Schnitzbauer, R. Scurrah, O. Serevina, P. Serralheiro, J. Sewards, M. Shackcloth, A. Shaw, A. Sheel, G. Sica, V. De Simone, A. Singh, Rabindra P Singh, B. Skelly, Henry G. Smith, Amir H. Sohail, D. Spalding, L. Springford, A. Ssentongo, P. Steinkamp, K. Stevens, G. Stewart, N. Stylianides, T. Sullivan, A. Taher, M. Tamimy, A. Tang, G. Tebala, F. J. Tejero-Pintor, M. Thaha, Amy Thomas, G. De Toma, F. la Torre, A. Torres, D. Townshend, I. Trout, S. Tucker, H. Ubhi, V. Vega, G. Velmahos, C. Velopulos, Y. Viswanath, A. Vivas, R. Wade, M. Wadley, J. Wall, Andrew M. Walters, O. Warren, C. Weerasinghe, R. Wilkin, K. Williams, S. Winter, J. Wormald, F. Wright, S. Xyda, A. Young, M. Youssef, F. B. Yousuf, H. El Youzouri, M. Zappa, E. Abate, H. Abdalaziz, M. Abdelkarim, Hossam Abdou, Ahmad Aboelkassem-Ibrahim, A. Abuown, F. Acebes-García, M. Acharya, M. Adamina, E. Addae-Boateng, R. Aftab, A. Agarwal, J. Aguilar, Yousra Ahmed, E. Aitken, M. Al-Azzawi, S. Al-Embideen, M. Al-Masri, H. Al-Najjar, A. Al-Sukaini, R. Alam, D. Alderson, Z. Aliyeva, Firas Aljanadi, M. Almasri, Paula Alonso-Ortuño, F. Altıntoprak, G. Amira, Rabbia Amjad, G. Anania, T. Andabaka, D. Angelou, S. Annamalai, V. Annessi, J. Anthoney, S. Anwar, M. Anwer, J. Aragón-Chamizo, A. Ardito, M. Arigoni, T. Armao, A. Arminio, L. Armstrong, A. Arnaud, P. Asaad, J. Ashcroft, C. Ashmore, A. Asqalan, E. Asti, E. Aubry, E. Aytaç, Esther Ayuso-Herrera, M. Baeza, M. Bailon-Cuadrado, B. Bakmaz, C. Baldi, E. Baldini, Stefano Baldo, M. Ballabio, I. Baloyiannis, G. Baltazar, F. Bàmbina, A. Bandiera, E. Barlow, R. Barmasse, C. Barmpagianni, G. Baronio, F. Barra, A. Bartsch, A. Basgaran, A. Basha, V. Bashkirova, M. Bastazza, R. Baumber, E. Belcher, A. Belvedere, I. Benítez-Linero, D. Bergeat, M. Bernasconi, A. Bhalla, N. Bhutiani, F. Bianco, P. Bisagni, I. Blake, R. Blanco‐Colino, Alma Blázquez-Martín, M. Boal, L. Bonavina, G. Bonavina, G. Bond-smith, K. Booth, F. Borges, F. Borghi, K. Bouchagier, G. Bourke, E. Boyle, G. Brachini, J. Brain, A. Brar, Lisa Breckles, F. Brétagnol, G. Brixton, P. Bruzzaniti, T. Bueser, N. Burnside, A. Caballero, Enrique Calcerrada-Alises, M. Callahan, E. Camarero, T. Campagnaro, M. Campanelli, M. Candiani, M. Cannoletta, M. Cantalejo-Díaz, H. Cao, P. Capelli, V. Capizzi, G. Carcano, F. Carissimi, M. Carlini, M. Carlucci, H. Carmichael, M. Carrasco, M. Carrillo, M. Carvello, M. Casati, C. Castoro, V. Catalán, S. Cavaleiro, P. Cellerino, G. Centinaio +499 moresemanticscholar +1 more sourceA nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...Jonas N. Kapp, Wouter P. R. Verdurmen, Jonas V. Schaefer, Kari Kopra, Gabriela Nagy‐Davidescu, Elodie Richard, Marie‐Julie Nokin, Patrick Ernst, Rastislav Tamaskovic, Martin Schwill, Ralph Degen, Claudia Scholl, David Santamaria, Andreas Plückthun +13 morewiley +1 more sourcePhase I Study Assessing the Pharmacokinetic Profile, Safety, and Tolerability of a Single Dose of Ceftazidime-Avibactam in Hospitalized Pediatric Patients. [PDF]
, 2016 This study aimed to investigate the pharmacokinetics (PK), safety, and tolerability of a single dose of ceftazidime-avibactam in pediatric patients. A phase I, multicenter, open-label PK study was conducted in pediatric patients hospitalized with an ...Armstrong, Jon, Arrieta, Antonio, Bishai, Raafat, Bradley, John S, Das, Shampa, Delair, Shirley, Edeki, Timi, Holmes, William C, Li, Jianguo, Moffett, Kathryn S, Mukundan, Deepa, Perez, Norma, Romero, José R, Speicher, David, Sullivan, Janice E, Zhou, Diansong +15 morecore
