Results 201 to 210 of about 4,513,718 (313)

Oral treatment for diabetes using α-glucosidase inhibitors was a risk factor for chronic obstructive pulmonary disease: a cohort study [PDF]

, 2020
Sheng‐Wen Wu, Yung-Chyuan Ho, Ci-Wen Luo, Hung-Yi Chen, Chun‐Hung Su, Yu‐Hsiang Kuan   +5 more
openalex   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Symptoms and Needs of Head and Neck Cancer Patients at Diagnosis of Incurability - Prevalences, Clinical Implications, and Feasibility of a Prospective Longitudinal Multicenter Cohort Study

, 2016
Bernd Alt‐Epping, Wiebke Seidel, J. Vogt, Anja Mehnert, Michael Thomas, Birgitt van Oorschot, Hendrik A. Wolff, Henning Schliephake, Martin Canis, Leif H. Dröge, Friedemann Nauck, Florian Lordick, on behalf of the Arbeitsgemeinschaft Palliativmedizin (APM) of the German Cancer Society (DKG)   +12 more
openalex   +2 more sources

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

FEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee, Jung Yoon Ho, In Sun Hwang, Youn Jin Choi   +3 more
wiley   +1 more source

Examination of Appendiceal Neoplasms-A Retrospective, Single-Centre, Cohort Study. [PDF]

Cancers (Basel)
Csonka B, Lantos T, Sejben A.
europepmc   +1 more source

Sexualised drug use among sexual minority young adults in the United States: The P18 cohort study

, 2018
Annie Ristuccia, Caleb LoSchiavo, Perry N. Halkitis, Farzana Kapadia   +3 more
openalex   +2 more sources

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Identification of Sarcopenic Obesity by Fat-to-Muscle Ratio in Older Adults: A Cohort Study. [PDF]

J Cachexia Sarcopenia Muscle
Kakita D, Harada K, Kurita S, Morikawa M, Nishijima C, Fujii K, Shimada H, Arai H.   +7 more
europepmc   +1 more source

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

Celiac Disease in Children with Idiopathic Nephrotic Syndrome-A Retrospective Cohort Study. [PDF]

J Clin Med
Ozimek A, Wasiak W, Albrecht P, Mizerska-Wasiak M.   +3 more
europepmc   +1 more source